Dansylleucine
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597442

CAS#: 1100-22-7

Description: Dansylleucine is a bioactive chemical.

Chemical Structure

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Dansylleucine
CAS# 1100-22-7
Instruction

Theoretical Analysis

MedKoo Cat#: 597442
Name: Dansylleucine
CAS#: 1100-22-7
Chemical Formula: C18H24N2O4S
Exact Mass: 364.15
Molecular Weight: 364.460
Elemental Analysis: C, 59.32; H, 6.64; N, 7.69; O, 17.56; S, 8.80

Price and Availability

Size Price Availability Quantity
100mg USD 250 2 Weeks
1g USD 650 2 Weeks
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Synonym: Dansylleucine; Dns-leucine; Dansyl-leucine;

IUPAC/Chemical Name: ((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-leucine

InChi Key: XBMQRPDOXIPUFG-HNNXBMFYSA-N

InChi Code: InChI=1S/C18H24N2O4S/c1-12(2)11-15(18(21)22)19-25(23,24)17-10-6-7-13-14(17)8-5-9-16(13)20(3)4/h5-10,12,15,19H,11H2,1-4H3,(H,21,22)/t15-/m0/s1

SMILES Code: CC(C)C[C@@H](C(O)=O)NS(=O)(C1=C2C=CC=C(N(C)C)C2=CC=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 364.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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2: Li Z, Hu C, Liu Y, Li Q, Fu Y, Chen Z. Facile preparation of ethanediamine-β- cyclodextrin modified capillary column for electrochromatographic enantioseparation of Dansyl amino acids. J Chromatogr A. 2021 Apr 26;1643:462082. doi: 10.1016/j.chroma.2021.462082. Epub 2021 Mar 18. PMID: 33780884.


3: Mauro G, Black N, Billiot E, Billiot F, Morris KF, Fang Y. Chiral Recognition of Dansyl Derivatives with an Amino Acid-Based Molecular Micelle: A Molecular Dynamics Investigation. Open J Phys Chem. 2021 May;11(2):64-86. doi: 10.4236/ojpc.2021.112004. Epub 2021 May 26. PMID: 34123572; PMCID: PMC8195262.


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6: Atamna IZ, Issaq HJ, Muschik GM, Janini GM. Optimization of resolution in capillary zone electrophoresis: combined effect of applied voltage and buffer concentration. J Chromatogr. 1991 Dec 27;588(1-2):315-20. doi: 10.1016/0021-9673(91)85039-i. PMID: 1818085.


7: Yin D, Xie C, Zhang L, Liu B, Zhou X, Wang P, Wu M. Development of a novel capillary electrophoresis chemiluminescence system for amino acid analysis. Luminescence. 2008 Nov-Dec;23(6):434-8. doi: 10.1002/bio.1076. PMID: 18800361.


8: Tamura A, Khademizadeh M, Tamura K, Masujima T. Direct observation of the separation process by the chromato-videoscope. J Pharm Biomed Anal. 1997 Jun;15(9-10):1477-82. doi: 10.1016/s0731-7085(97)00018-6. PMID: 9226578.


9: Wagner SR, Liu DK. Adrenalectomy alters acid-soluble leucine pool in rat kidney and heart. Int J Biochem. 1981;13(4):501-7. doi: 10.1016/0020-711x(81)90124-5. PMID: 7238983.