L 687384

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MedKoo CAT#: 596631

CAS#: 95417-67-7

Description: L 687384 is a high-affinity sigma receptor ligand.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-03-29. Prices are subject to change without notice.

L 687384 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596631
Name: L 687384
CAS#: 95417-67-7
Chemical Formula: C21H25N
Exact Mass: 291.1987
Molecular Weight: 291.43
Elemental Analysis: C, 86.55; H, 8.65; N, 4.81


Synonym: L 687384; L-687384; L687384; L-687,384; L 687,384; L687,384;

IUPAC/Chemical Name: 1'-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4'-piperidine]

InChi Key: MLDCBJPLHBPJET-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2

SMILES Code: C12=C(C3(CCN(CC4=CC=CC=C4)CC3)CCC2)C=CC=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Couture S, Debonnel G. Some of the effects of the selective sigma ligand (+)pentazocine are mediated via a naloxone-sensitive receptor. Synapse. 2001 Mar 15;39(4):323-31. PubMed PMID: 11169783.

2: Bergeron R, Debonnel G. Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors. Psychopharmacology (Berl). 1997 Feb;129(3):215-24. PubMed PMID: 9084059.

3: McLarnon J, Sawyer D, Church J. The actions of L-687,384, a sigma receptor ligand, on NMDA-induced currents in cultured rat hippocampal pyramidal neurons. Neurosci Lett. 1994 Jun 20;174(2):181-4. PubMed PMID: 7526288.