Hexapropymate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596506

CAS#: 358-52-1

Description: Hexapropymate is a hypnotic drug.

Chemical Structure

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Hexapropymate
CAS# 358-52-1
Instruction

Theoretical Analysis

MedKoo Cat#: 596506
Name: Hexapropymate
CAS#: 358-52-1
Chemical Formula: C10H15NO2
Exact Mass: 181.11
Molecular Weight: 181.230
Elemental Analysis: C, 66.27; H, 8.34; N, 7.73; O, 17.66

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Hexapropymate; Esapropimato; Lunamin; L 2103; L-2103; L2103; NSC 169094; NSC-169094; NSC169094;

IUPAC/Chemical Name: 1-(prop-2-yn-1-yl)cyclohexyl carbamate

InChi Key: MIRHIEAGDGUXKL-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H15NO2/c1-2-6-10(13-9(11)12)7-4-3-5-8-10/h1H,3-8H2,(H2,11,12)

SMILES Code: NC(OC1(CC#C)CCCCC1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 181.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gustafsson LL, Berg A, Magnusson A, Malmlund HO, Sandell BM, Stig R. Hexapropymate self-poisoning causes severe and long-lasting clinical symptoms. Med Toxicol Adverse Drug Exp. 1989 Jul-Aug;4(4):295-301. PubMed PMID: 2770531.

2: Leyssens L, van Boven M, Daenens P. Biotransformation of hexapropymate in man. Part 2: Isolation and identification of metabolites. Pharmazie. 1984 Feb;39(2):114-7. PubMed PMID: 6718477.

3: Robbins G, Brown AK. Hexapropymate self-poisoning. Br Med J. 1978 Jun 17;1(6127):1593. PubMed PMID: 656827; PubMed Central PMCID: PMC1605342.

4: Hassoun A, van Binst R, Vandendriessche M. [A rapid and simple method for the qualitative and quantitative determination of hexapropymate in biological fluids and organs (author's transl)]. Toxicol Eur Res. 1978 May;1(3):185-8. French. PubMed PMID: 741478.

5: Risberg AM, Risberg J, Ingvar DH. [Effects of hexapropymate on sleep in normal humans, measured with a polygraphic method]. Sem Hop Ther. 1975 Feb;51(2):99-104. French. PubMed PMID: 1099650.

6: Siguier F, Godeau P, Vergoz D, Imbert JC, Herreman G, Reinert P. [Immuno-allergic thrombopenic purpura caused by hexapropymate sensitization]. Ann Med Interne (Paris). 1971 Mar;122(3):435-8. French. PubMed PMID: 5314641.

7: Favarel-Garrigues B, Bourgeois M, Vincent JD. [Polygraphic study of night sleep under the effects of hexapropymate]. Bord Med. 1971 Jan;4(1):255-8 passim. French. PubMed PMID: 5553039.

8: Noirfalise A. [5 cases of suspected hexapropymate poisoning]. Eur J Toxicol. 1971 Jan-Feb;4(1):50-2. French. PubMed PMID: 5092668.

9: Favarel-Garrigue B, Bourgeois M. [Polygraphic study of night sleep under hexapropymate]. Presse Med. 1970 Nov 21;78(49):2201-2. French. PubMed PMID: 4320460.

10: CANLORBE P, BORNICHE P. [Pediatric indications for a synthetic non-barbituric hypnotic: hexapropymate]. Ann Pediatr (Paris). 1962 Dec 2;9:632-3. French. PubMed PMID: 14018306.