WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596004
CAS#: 65323-80-0
Description: J 628 is a synthetic "impeded" estrogen derivative. It has some postcoital antifertility activity and estrogenicity in mice.
MedKoo Cat#: 596004
Name: J 628
CAS#: 65323-80-0
Chemical Formula: C23H31NO4S
Exact Mass: 417.1974
Molecular Weight: 417.56
Elemental Analysis: C, 66.16; H, 7.48; N, 3.35; O, 15.33; S, 7.68
This product is not in stock, which may be available by custom synthesis.
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Synonym: J628; J 628; J-628;
IUPAC/Chemical Name: (8R,9S,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl dimethylsulfamate
InChi Key: ZBACBJUPJKFZST-MHMIHQHRSA-N
InChi Code: InChI=1S/C23H31NO4S/c1-5-22-13-11-19-18-10-8-17(28-29(26,27)24(3)4)15-16(18)7-9-20(19)21(22)12-14-23(22,25)6-2/h2,8,10,15,19-21,25H,5,7,9,11-14H2,1,3-4H3/t19-,20-,21+,22+,23-/m1/s1
SMILES Code: C#C[C@@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=C(C=CC(OS(=O)(N(C)C)=O)=C4)[C@@]3([H])CC[C@]12CC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 417.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Oettel M, Draffehn J, Koch M, Kurischko A, Ohme E, Strecke J, Tiroke I. Relationship between uterotrophic and interceptive activities of steroidal estrogens. Endokrinologie. 1978 Apr;72(1):25-35. PubMed PMID: 567577.
2: Jemilev ZA, Komor A, Schubert K, Ponsold K, Grosse P, Oettel M, Strecke J. [Chromosome analysis in baboons born following the use of potential, postovulatory, fertility-inhibiting steroids]. Zentralbl Gynakol. 1978;100(6):337-40. German. PubMed PMID: 654667.
