WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596004
CAS#: 65323-80-0
Description: J 628 is a synthetic "impeded" estrogen derivative. It has some postcoital antifertility activity and estrogenicity in mice.
MedKoo Cat#: 596004
Name: J 628
CAS#: 65323-80-0
Chemical Formula: C23H31NO4S
Exact Mass: 417.1974
Molecular Weight: 417.56
Elemental Analysis: C, 66.16; H, 7.48; N, 3.35; O, 15.33; S, 7.68
J 628 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.
Synonym: J628; J 628; J-628;
IUPAC/Chemical Name: (8R,9S,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl dimethylsulfamate
InChi Key: ZBACBJUPJKFZST-MHMIHQHRSA-N
InChi Code: InChI=1S/C23H31NO4S/c1-5-22-13-11-19-18-10-8-17(28-29(26,27)24(3)4)15-16(18)7-9-20(19)21(22)12-14-23(22,25)6-2/h2,8,10,15,19-21,25H,5,7,9,11-14H2,1,3-4H3/t19-,20-,21+,22+,23-/m1/s1
SMILES Code: C#C[C@@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=C(C=CC(OS(=O)(N(C)C)=O)=C4)[C@@]3([H])CC[C@]12CC
The following data is based on the product molecular weight 417.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Oettel M, Draffehn J, Koch M, Kurischko A, Ohme E, Strecke J, Tiroke I. Relationship between uterotrophic and interceptive activities of steroidal estrogens. Endokrinologie. 1978 Apr;72(1):25-35. PubMed PMID: 567577.
2: Jemilev ZA, Komor A, Schubert K, Ponsold K, Grosse P, Oettel M, Strecke J. [Chromosome analysis in baboons born following the use of potential, postovulatory, fertility-inhibiting steroids]. Zentralbl Gynakol. 1978;100(6):337-40. German. PubMed PMID: 654667.