Xylure

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341503

CAS#: 70523-31-8

Description: Xylure is a biochemical.


Price and Availability

Size
Price

Size
Price

Size
Price

Xylure is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 341503
Name: Xylure
CAS#: 70523-31-8
Chemical Formula: C12H20N2O5Si
Exact Mass: 300.1141
Molecular Weight: 300.386
Elemental Analysis: C, 47.98; H, 6.71; N, 9.33; O, 26.63; Si, 9.35


Synonym: Xylure.

IUPAC/Chemical Name: Uridine, 2'-deoxy-5-(trimethylsilyl)-

InChi Key: DZEOQTVJWBLBOT-QXFUBDJGSA-N

InChi Code: InChI=1S/C12H20N2O5Si/c1-20(2,3)9-5-14(12(18)13-11(9)17)10-4-7(16)8(6-15)19-10/h5,7-8,10,15-16H,4,6H2,1-3H3,(H,13,17,18)/t7-,8+,10+/m0/s1

SMILES Code: OC[C@@H]1[C@H](C[C@H](N2C(NC(C([Si](C)(C)C)=C2)=O)=O)O1)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Ektova LV, Iartseva IV, Khorosheva EV, Ivanova TP, Iavorskaia NP, Mel'nik SIa. [Synthesis and biological properties of pyrimidine 2'-deoxynucleosides modified by a residue of quinaldic acid]. Bioorg Khim. 1995 Aug;21(8):625-31. Russian. PubMed PMID: 8540903.

2: Bektemirov TA, Chekunova ZV, Andzhaparidze OG. [Antiviral activity of the 1-alpha- and beta-desoxy-D-ribofuranosides of 5-trimethylsilyl uracil]. Vopr Virusol. 1987 Jan-Feb;32(1):114-6. Russian. PubMed PMID: 3033901.

3: Chekunova EV, Marennikova SS, Mel'nik SIa, Preobrazhenskaia MN, Zaguliaeva OA. [Antiherpetic activity of xylure]. Vopr Virusol. 1985 Jul-Aug;30(4):444-6. Russian. PubMed PMID: 3904209.

4: Zhirnov OP, Ovcharenko AV, Bukrinskaia AG. [Blocking of Sindbis virus replication in the body of infected mice using an inhibitor of chymotrypsin-like proteases]. Vopr Virusol. 1985 Jul-Aug;30(4):450-3. Russian. PubMed PMID: 2998094.