BC12-4

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526489

CAS#: 94212-33-6

Description: BC12-4 is a novel potent inhibitor of IL-2 secretion, demonstrating potent immunomodulatory activity.


Price and Availability

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Price

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Price

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BC12-4 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 526489
Name: BC12-4
CAS#: 94212-33-6
Chemical Formula: C19H14N2O3
Exact Mass: 318.1
Molecular Weight: 318.33
Elemental Analysis: C, 71.69; H, 4.43; N, 8.80; O, 15.08


Synonym: BC12-4

IUPAC/Chemical Name: 1-Phenyl-5-(3-phenyl-2-propen-1-ylidene)-2,4,6(1H,3H,5H)-pyrimidinetrione

InChi Key: COXDMRSXWPMFJU-NJKRNUQASA-N

InChi Code: InChI=1S/C19H14N2O3/c22-17-16(13-7-10-14-8-3-1-4-9-14)18(23)21(19(24)20-17)15-11-5-2-6-12-15/h1-13H,(H,20,22,24)/b10-7+,16-13+

SMILES Code: O=C1NC(/C(C(N1C2=CC=CC=C2)=O)=C\C=C\C3=CC=CC=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Xu C, Wyman AR, Alaamery MA, Argueta SA, Ivey FD, Meyers JA, Lerner A, Burdo TH, Connolly T, Hoffman CS, Chiles TC. Anti-inflammatory effects of novel barbituric acid derivatives in T lymphocytes. Int Immunopharmacol. 2016 Sep;38:223-32. doi: 10.1016/j.intimp.2016.06.004. Epub 2016 Jun 13. PubMed PMID: 27302770.

2: Khadse SV, Bajaj G, Vibhakar P, Nainani P, Ahuja R, Deep G. Evaluation of Specificity and Sensitivity of Oral Fluid for Diagnosis of Hepatitis B. J Clin Diagn Res. 2016 Jan;10(1):BC12-4. doi: 10.7860/JCDR/2016/17319.7107. Epub 2016 Jan 1. PubMed PMID: 26894057; PubMed Central PMCID: PMC4740584.