Src I1 | CAS#179248-59-0

Src I1
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WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407408

CAS#: 179248-59-0

Description: Src I1 is a potent, competitive dual site (ATP- and peptide-binding) Src kinase inhibitor.

Chemical Structure

Src I1

CAS# 179248-59-0

Product data Instruction

Theoretical Analysis

MedKoo Cat#: 407408
Name: Src I1
CAS#: 179248-59-0
Chemical Formula: C22H19N3O3
Exact Mass: 373.14
Molecular Weight: 373.412
Elemental Analysis: C, 70.76; H, 5.13; N, 11.25; O, 12.85

Price and Availability

Size	Price	Availability
200mg	USD 650	2 Weeks
500mg	USD 1250	2 Weeks
1g	USD 2250	2 Weeks
2g	USD 4250	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Related CAS #: Src I1; Src I-1; SrcI1.

Synonym: Src I1; Src I-1; SrcI1.

IUPAC/Chemical Name: 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine

InChi Key: DMWVGXGXHPOEPT-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H19N3O3/c1-26-20-12-18-19(13-21(20)27-2)23-14-24-22(18)25-15-8-10-17(11-9-15)28-16-6-4-3-5-7-16/h3-14H,1-2H3,(H,23,24,25)

SMILES Code: COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:

Product Data

Instruction:

View handling instruction

Biological target:	Src I1 is an Src kinase inhibitor (IC50s = 44 and 88 nM for Src and Lck, respectively).
In vitro activity:	To be determined
In vivo activity:	To be determined

Solubility Data

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	9.1	24.34

Preparing Stock Solutions

The following data is based on the product molecular weight 373.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:	To be determined
In vitro protocol:	To be determined
In vivo protocol:	To be determined

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