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Pirtobrutinib, also known as LOXO-305 and LY 3527727, is a Bruton's tyrosine kinase (BTK) inhibitor and...
Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited...
OPC-21268 is a vasopressin 1 receptor antagonist potentially for the treatment of heart failure and hypertension.
MK-8722 is a potent pan-AMPK activator. MK-8722 improves glucose homeostasis but induces cardiac hypertrophy. In...
NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates...
LY2828360 is a novel potent, selective, and efficacious CB2 agonist.
CAS#: 1616632-77-9 (free base)
VUN32779, also known as...
LY-2608204 is an activator of glucokinase (GK) with an EC50 value of 42 nM. LY2608204 decreases plasma glucose in a...
GTPL6019, also know nas IUN54940, DGFR Tyrosine Kinase Inhibitor III, is a PDGFR inhibitor with potential anticancer...
WUN55267, also known as GPR40/FFAR1 modulator 1, is an agonist and an allosteric modulator for Gq-coupled free fatty...
LVN84663 is a useful reagent for determination of blood coagulating protease. It was first described in patent DE...
CAS#: 117946-91-5 (free base)
Luzindole, also known as N-0774, and N-acetyl-2-benzyltryptamine, is a melatonin receptor antagonist that...
FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant...
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50 = 0.2 nM. LSZ102 demonstrated IC50...
VV116, also known as JT001, is an oral drug candidate of nucleoside analog against SARS-CoV-2. VV116 is a deuterated,...
CAS#: 55750-05-5 (HCl)
Caroverine is a nonselective NMDA and AMPA glutamate receptor antagonist, also acting as a class B...
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M...
GSK215 is a potent, selective, FAK-degrading Proteolysis Targeting Chimera (PROTAC) based on a binder for the VHL E3...
CAS#: 181147-28-4 (HCl)
YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity. YCN47284 was first reported in WO...
Lomitapide free base
CAS#: 182431-12-5 (free base)
Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozygous familial...
MRTX1133 is a potent and selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12D protein in both active and...
LMN75224 is a phosphodiesterase 1 inhibitors useful for treatment of neurological and psychiatric disorder. LMN75224...
LML134 is an orally active and high selective Histamine 3 receptor (H3R) inverse agonist with Kis of 0.3 nM and 12 nM...
AZD6703 free base
CAS#: 851845-37-9 (free base)
AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase...
FR901464 is a potent spliceosome inhibitor and a potential agent for colorectal cancer in combination therapy.