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Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a...
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases...
GABOB, also known as γ-Amino-β-hydroxybutyric acid, β-hydroxy-γ-aminobutyric acid, β-hydroxy-GABA, is an...
HSF1A is an activator of Heat shock transcription factor 1 (HSF1).
HS-1793 is a resveratrol analogue. HS-1793 downregulates the expression of hypoxia-induced HIF-1 and VEGF and...
HMN-154 is a benzenesulfonamide anticancer agent. HMN-154 inhibits DNA binding of NF-Y to the human major...
Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well...
Elimusertib free base
CAS#: 1876467-74-1 (free base)
Elimusertib, also known as BAY-1895344, is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor...
HBX19818 is a selective inhibitor of USP7.
CAS#: 926037-48-1 (free base)
Radotinib, also known as IY-5511, is an orally available, a second-generation tyrosine kinase inhibitor of Bcr-Abl...
GNF-7 is a type-II T315I inhibitor. GNF-7 inhibits Ack1 and germinal center kinase (GCK). GNF-7 displayed...
H3B-5942 free base
CAS#: 2052128-15-9 (free base)
H3B-5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist. In vitro comparisons...
GW806742X is a potent MLKL inhibitor, also a human and murine necroptosis inhibitor. GW806742X binds the MLKL...
GW284543, also known as UNC10225170;, is a potent and selective MEK5 inhibitor with the potential for cancer...
GW280264X is an ADAM17 inhibitor.
XL092 is an ATP-competitive inhibitor of multiple RTKs including MET, VEGFR2, AXL and MER, with IC50 values in...
GSK805, also known as ROR gamma-t-IN-1, is a potent, orally bioavailable retinoid-related orphan receptor gamma t...
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain,...
GSK620 is a Potent, selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2)...
HM43239 is an orally active small molecule inhibitor of FLT3 that selectively inhibits not only FLT3 wild type, ITD...
CAS#: 1610358-53-6 (racemate)
BAY-1251152 racemate, also known as (±)-BAY-1251152, is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and...
GSK4112 is a selective Rev-Erbα agonist (EC50 = 250 nM). GSK4112 enhances recruitment of nuclear receptor...
GSK3i XIII is an ATP-binding site inhibitor of GSK-3.
SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited...
GSK3039294 is an orally available small molecule inhibitor of serum amyloid P component (SAP) binding to amyloid...