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CAS#: 849675-87-2 (mesylate)
Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral...
ND-646 is-an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 that prevents ACC subunit dimerization-to suppress...
NCT-501 is a potent ALDH1A1 inhibitor. Aldehyde dehydrogenases (ALDHs) metabolize reactive aldehydes and possess...
NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
NCGC00135472 is an gonist for human Resolvin D1 Receptor DRV1 with pro-resolving functions.
NBMPR, also known as S-4-nitrophenylmethyl-6-thioinosine, is a nucleoside analog that competitively inhibits the...
Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in...
NB-598 free base
CAS#: 131060-14-5 (free base)
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis...
Navoximod free base
CAS#: 1402837-78-8 (free base)
Navoximod, also known as IDO-IN-7 and NLG-1488, is an indoleamine 2,3-dioxygenase (IDO) inhibitor. It is also used...
Grassofermata, also known as NAV-2729, is a selective ARF6 inhibitor (IC50 = 1.0 μM). Blocking ARF6 with a...
ASTX029 is a highly potent and selective dual-mechanism ERK inhibitor. ASTX029 inhibits both ERK catalytic activity...
Rineterkib free base
CAS#: 1715025-32-3 (free base)
Rineterkib, also known as LTT-462 or ERK-IN-1, is a ERK1/2 inhibitor which has demonstrated preclinical activity in...
NAN190 free base
CAS#: 102392-05-2 (free base)
NAN-190 is a mixed antagonist and partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. NAN-190...
Namodenoson, also known as 2-Cl-IB-MECA and CF-102, is an orally bioavailable, synthetic, highly selective adenosine...
SGC-SMARCA-BRDVIII is a selective and high affinity SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomains...
BMS-223131 is a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels. BMS-223131 effectively reduced...
Asulacrine free base
CAS#: 80841-47-0 (free base)
Asulacrine, also known as CI-921; NSC-343499; SN-21407, is a topoisomerase ll inhibitor with antineoplastic...
CAS#: 112892-51-0 (HBr)
Alentemol, also known as U-66444B abd alentamol, is a selective dopamine autoreceptor agonist described as an...
CAS#: 459814-89-2 (free base)
AZD1236 is a potent and reversible inhibitor of human MMP-9 and MMP-12 (IC50 = 4.5 and 6.1nM, respectively), with...
CAS#: 28643-80-3 (sodium)
Nigericin is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It...
LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of...
CAS#: 65473-14-5 (HCl); 65472-88-0 (free base).
Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis...
Anaxirone is a synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA...
Bemitradine is a diuretic antihypertensive agent.
N6022 is a potent, selective, reversible, and efficacious S-nitrosoglutathione reductase (GSNOR) inhibitor and is...