Newest Products

GNE-781

CAT#: 407813
CAS#: 1936422-33-1

GNE-781 is a Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response...

Telacebec free base

CAT#: 555932
CAS#: 1334719-95-7 (free base)

Telacebec, also known as Q-203, is an antituberculosis agent and a potent inhibitor of mycobacterium tuberculosis...

PY-60

CAT#: 465543
CAS#: unknown

PY-60 is a novel activator of YAP, promoting expansion of epidermal keratinocytes ex vivo and in vivo, targeting...

Entrectinib

CAT#: 206181
CAS#: 1108743-60-7

Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well...

Beclamide

CAT#: 535292
CAS#: 501-68-8

Beclamide is a drug that possesses anticonvulsant activity. It is no longer used. Beclamide is possibly metabolized...

BI-847325

CAT#: 206543
CAS#: 1207293-36-4

BI-847325 is an orally available dual inhibitor of mitogen-activated protein kinase kinase (MEK) and Aurora kinases,...

BI-3406

CAT#: 207113
CAS#: 2230836-55-0

BI-3406 is Potent & Selective SOS1::KRAS Inhibitor (IC50=5 nM), which Opens a New Approach for Treating KRAS-Driven...

MSA-2

CAT#: 463682
CAS#: 129425-81-6

MSA 2 is a non-nucleotide STING agonist. It exhibits antitumor activity and stimulates interferon-β secretion in...

TPX-0022

CAT#: 408118
CAS#: 2271119-26-5

TPX-0022, also known as CSF1R-IN-2, is an orally bioavailable multi-targeted kinase inhibitor with a novel...

SNDX-5613

CAT#: 462564
CAS#: 2169919-21-3

SNDX-5613 is a potent and specific Menin-MLL inhibitor. It can be used for the research of MLL-rearranged (MLL-r)...

QQN05022

CAT#: 555037
CAS#: 2565705-02-2

QQN05022, also known as Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor....

AZD8186

CAT#: 406260
CAS#: 1627494-13-6

AZD8186 is and inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential antineoplastic...

RSM-932A

CAT#: 206474
CAS#: 850807-63-5

RSM-932A, also known as TCD-717, is a ChoKα inhibitor, which targets the human choline kinase alpha, an enzyme...

Selgantolimod

CAT#: 584818
CAS#: 2004677-13-6

Selgantolimod, also known as GS-9688, is a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment...

CGP53353

CAT#: 513675
CAS#: 145915-60-2

CGP53353 is a selective inhibitor of PKCβII (IC50 values are 0.41 and 3.8 μM for PKCβII and PKCβI respectively)....

HLY78

CAT#: 556065
CAS#: 854847-61-3

HLY78 is an activator of the Wnt/β-Catenin signaling pathway. HLY78 protects blood-brain barrier integrity through...

YQ128

CAT#: 556036
CAS#: 2454246-18-3

YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of...

Proxalutamide

CAT#: 527507
CAS#: 1398046-21-3

Proxalutamide, also known as GT-0918, is an androgen receptor antagonist potentially for the treatment of metastatic...

JNJ-63576253

CAT#: 207041
CAS#: 2110426-27-0 (free base)

JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically...

JNJ-63576253 HCl

CAT#: 207173
CAS#: 2110428-64-1 (HCl)

JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically...

Etrumadenant

CAT#: 207077
CAS#: 2239273-34-6

Etrumadenant, also known as AB928, is a dual antagonist of the A2aR and A2bR adenosine receptors, leads to greater...

ONC212

CAT#: 206933
CAS#: 1807861-48-8

ONC212 is a fluorinated-ONC201 analogue and GPR132 agonist, which shows preclinical efficacy in melanoma and...

NCGC00244536

CAT#: 561403
CAS#: 2003260-55-5

KDM4B-IN-B3, also know as NCGC00244536, is a novel KDM4 inhibitor. KDM4B-IN-B3 inhibits the in vivo growth of...

BVT948

CAT#: 563502
CAS#: 39674-97-0

BVT948 is a protein tyrosine phosphatases (PTP) inhibitor (IC50 = 0.09 - 1.7 μM). BVT948 inhibits NF-κB activation by...

AZD4635

CAT#: 206930
CAS#: 1321514-06-0

AZD-4635, also known as HTL-1071, is an orally available, small molecule adenosine A2A receptor antagonist.