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VPC 24191 is a sphingosine 1-phosphate (S1P1/3) receptor agonist.
VPC 31143 (R)
VPC 31143 (R) is a biochemical
VPC 32183 (S)
VPC 32183 (S) is a competitive antagonist at the LPA1 and LPA3 receptors. VPC 32183 is devoid of agonist activity at...
VPC-70063 is a Myc-Max inhibitor. VPC-70067 is a close analog of the previously identified Myc inhibitor 10058-F4....
VPS34-IN1 is a potent and selective Vps34 inhibitor with potential anticancer activity. VPS34-IN1 inhibits Vps34 with...
Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34.
VR23 is a potent and selective inhibitor of trypsin-like proteasomes (IC50 = 1 nmol/L), chymotrypsin-like proteasomes...
VRT-043198, the active metabolite of VX-765 (Belnacasan), is a Caspase inhibitor. VRT-043198 exhibits 100- to...
VRT-532 is a CFTR modulator for the treatment of cystic fibrosis.
VS-5584, also known as SB2343, is a potent and selective inhibitor of both phosphatidylinositol 3 kinase (PI3K) and...
VSN35111; , also known as BACE-1 Inhibitor, β-Secretase Inhibitor IV, is an inhibitor of β-site amyloid protein...
CAS#: 2417718-25-1 (S-isomer)
VT-104 is a potent and selective TEAD Auto-palmitoylation inhibitor that Inhibits Proliferation and Tumor Growth of...
CAS#: 2417718-63-7 (S-isomer)
VT-107 is a potent and selective TEAD Auto-palmitoylation inhibitor that Inhibits Proliferation and Tumor Growth of...
VTP-27999 is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). VTP-27999 demonstrated excellent...
VTP50469 free base
CAS#: 2169916-18-9 (free base)
VTP-50469 is a novel, potent, selective, orally-available Menin MLL1 inhibitor, being effectively against...
VTX-27 is a novel potent and selective PKCθ inhibitor.
VU0071063 is an activator of Kir6.2/SUR1.
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator...
VU0134992 is a selective Kir4.1 potassium channel pore blocker.
VU0152100 is a highly selective M4 positive allosteric modulator (PAM) that exerts central effects after systemic...
VU0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC₅₀ = 798 and 693 nM at...
VU-0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor.
VU0238429 is a selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5,...
VU0238441 is a potent agonist of human Muscarinic acetylcholine receptor M5 with EC50 of 2.1 μM.
VU0240551 is an inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in...