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VU0071063 is an activator of Kir6.2/SUR1.
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator...
VU0134992 is a selective Kir4.1 potassium channel pore blocker.
VU0152100 is a highly selective M4 positive allosteric modulator (PAM) that exerts central effects after systemic...
VU0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC₅₀ = 798 and 693 nM at...
VU-0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor.
VU0238429 is a selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5,...
VU0238441 is a potent agonist of human Muscarinic acetylcholine receptor M5 with EC50 of 2.1 μM.
VU0240551 is an inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in...
VU0255035 is a highly selective muscarinic M1 antagonist (Ki = 14.87 nM). VU0255035 targets the M1 orthosteric site...
VU0285655-1 or APV (1158347-73-9) is a phospholipase D2 (PLD2) inhibitor. It induces autophagy in colorectal cancer...
VU0285683 is a negative allosteric modulator of mGlu5 receptors. VU0285683 acts as a full antagonist and blocks the...
VU0357017, also known as CID 25010775, is a subtype-selective M1 muscarinic acetylcholine allosteric agonist.
VU0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that...
VU 0361737, also known as ML128, is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and...
VU0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
VU0364739, also known as ML271, is a potent and selective allosteric PLD2 Inhibitor (cellular PLD1, IC50 = 1,500 nM,...
VU0364770 is a Positive allosteric modulator at mGlu4 receptors (EC50 = 290 nM in mGlu4-expressing HEK 293 cells)....
VU0365114 is a positive allosteric modulator of M5 muscarinic acetylcholine receptors (mAChRs). It increases...
VU0409106 is a potent and selective inhibitor of mGlu5.
VU0409551, also known as JNJ-46778212, is orally bioavailable metabotropic glutamate receptor subtype 5 (mGlu5)...
VU0422288, also known as ML 396, is a positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4,...
VU0424465 is a potent mGlu5 positive allosteric modulator and agonist
VU0463271 inhibits co-transporter KCC2.
VU0463597, also known as ML-289, is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold...