Featured Products

VTP-27999 TFA

CAT#: 526712
CAS#: 1013937-63-7

VTP-27999 is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). VTP-27999 demonstrated excellent...

VTP50469 free base

CAT#: 533776
CAS#: 2169916-18-9 (free base)

VTP-50469 is a novel, potent, selective, orally-available Menin MLL1 inhibitor, being effectively against...

VTX-27

CAT#: 533784
CAS#: 1321924-70-2

VTX-27 is a novel potent and selective PKCθ inhibitor.

VU0071063

CAT#: 563099
CAS#: 333415-38-6

VU0071063 is an activator of Kir6.2/SUR1.

VU0119498

CAT#: 532894
CAS#: 79183-37-2

VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator...

VU0134992

CAT#: 564653
CAS#: 755002-90-5

VU0134992 is a selective Kir4.1 potassium channel pore blocker.

VU0152100

CAT#: 530354
CAS#: 409351-28-6

VU0152100 is a highly selective M4 positive allosteric modulator (PAM) that exerts central effects after systemic...

VU0155041

CAT#: 532896
CAS#: 1093757-42-6

VU0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC₅₀ = 798 and 693 nM at...

VU-0155069

CAT#: 563158
CAS#: 1130067-06-9

VU-0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor.

VU0238429

CAT#: 532897
CAS#: 1160247-92-6

VU0238429 is a selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5,...

VU0238441

CAT#: 555870
CAS#: 85511-68-8

VU0238441 is a potent agonist of human Muscarinic acetylcholine receptor M5 with EC50 of 2.1 μM.

VU0240551

CAT#: 532899
CAS#: 893990-34-6

VU0240551 is an inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in...

VU0255035

CAT#: 532900
CAS#: 1135243-19-4

VU0255035 is a highly selective muscarinic M1 antagonist (Ki = 14.87 nM). VU0255035 targets the M1 orthosteric site...

VU0285655-1

CAT#: 412719
CAS#: 1158347-73-9

VU0285655-1 or APV (1158347-73-9) is a phospholipase D2 (PLD2) inhibitor. It induces autophagy in colorectal cancer...

VU0285683

CAT#: 532901
CAS#: 327056-22-4

VU0285683 is a negative allosteric modulator of mGlu5 receptors. VU0285683 acts as a full antagonist and blocks the...

VU0357017 HCl

CAT#: 531332
CAS#: 1135242-13-5

VU0357017, also known as CID 25010775, is a subtype-selective M1 muscarinic acetylcholine allosteric agonist.

VU0357121

CAT#: 526781
CAS#: 433967-28-3

VU0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that...

VU 0361737

CAT#: 531331
CAS#: 1161205-04-4

VU 0361737, also known as ML128, is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and...

VU0364439

CAT#: 526782
CAS#: 1246086-78-1

VU0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).

VU0364739 HCl

CAT#: 530614
CAS#: 1244640-48-9

VU0364739, also known as ML271, is a potent and selective allosteric PLD2 Inhibitor (cellular PLD1, IC50 = 1,500 nM,...

VU0364770

CAT#: 530372
CAS#: 61350-00-3

VU0364770 is a Positive allosteric modulator at mGlu4 receptors (EC50 = 290 nM in mGlu4-expressing HEK 293 cells)....

VU0365114

CAT#: 465306
CAS#: 1208222-39-2

VU0365114 is a positive allosteric modulator of M5 muscarinic acetylcholine receptors (mAChRs). It increases...

VU0409106

CAT#: 525254
CAS#: 1276617-62-9

VU0409106 is a potent and selective inhibitor of mGlu5.

VU0409551

CAT#: 522363
CAS#: 1363281-27-9

VU0409551, also known as JNJ-46778212, is orally bioavailable metabotropic glutamate receptor subtype 5 (mGlu5)...

VU0422288

CAT#: 530925
CAS#: 1630936-95-6

VU0422288, also known as ML 396, is a positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4,...