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XL092 is an ATP-competitive inhibitor of multiple RTKs including MET, VEGFR2, AXL and MER, with IC50 values in...
XL147-II is an ATP-competitive inhibitor of class I PI3K isoforms. It acts by abrogating Akt and S6 phosphorylation...
CAS#: 2417089-74-6 (S-isomer)
XL177A is a potent USP7 inhibitor. XL177A irreversibly inhibits USP7 with sub-nM potency and selectivity across the...
XL228 is a synthetic molecule that targets multiple tyrosine kinases with potential antineoplastic activity. Tyrosine...
XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the...
XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with...
XMD16-5 is a tyrosine kinase nonreceptor 2(TNK2) inhibitor. TNK2 mutations have been found in renal cancer cells and...
CAS#: 1628614-50-5 (free base)
XMD-17-51 is a potent and selective NUAK1 inhibitor.
XMD8-85, also known as ERK5-IN-1, exhibits potent inhibition of ERK5 and LRRK2.
XMD8-87 is a TNK2 inhibitor. XMD8-87 showed activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5...
XMD8-92 is an ERK5/BMK1 inhibitor and also BRD4 inhibitor. XMD8-92 inhibits pancreatic tumor xenograft growth via a...
XMU-MP-1 is a potent and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM,...
XP-59 is a potent inhibitor of the SARS-CoV Mpro
XRK3F2 is an inhibitor of signaling via the ZZ domain of p62 (Sequestosome 1), blocking tumor necrosis factor (TNF)...
XRP44X is a potent Ras-Net (Elk-3) pathway inhibitor.
XUM 00724, also known as N-(hydroxy-PEG2)-N'-(azide-PEG3)-Cy5 is a PEG derivative containing a cyanine dye with...
XUM 00856, also known as N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a cyanine derivative with...
XUM 00927, also known as N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a cyanine labeled PEG derivative with...
XUN 02157, also known as N-(t-butyl ester-PEG3)-N-bis(PEG3-azide) is a branched PEG derivative with two terminal...
XUN-08053 is a functionalized cereblon ligand for PROTAC® research and development. It incorporates an E3 ligase...
XUN-29022 is a functionalized cereblon ligand for PROTAC® research and development. It incorporates an E3 ligase...
XUN 35237, also known as Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable PEG Linker. PEG Linkers may be useful in...
XUN37434, also known as 3,4-Dibromo-Mal-PEG2-Boc-Amine is a PEG Linker. This product has no formal name at the...
XUN 49307, also known as Propargyl-PEG3-Tos is a PEG derivative containing a tosyl group and a propargyl group. The...
XY 018 is a RORγ antagonist that suppresses androgen receptor expression in prostate cancer cell lines and inhibits...