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A1899 is a potent and selective TASK-1 and TASK-3 antagonist.
A-192621 is an endothelin-B antagonist. A-192621 markedly enhanced MAP, TPR, and mesenteric, and the renal...
A-196 is the first potent and selective chemical probe for SUV420H1 and SUV420H2. The in vitro activity of A-196...
A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM...
CAS#: 22816-60-0 (HCl)
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant....
A2-32-01 is a HsClpP antagonist.
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TWIK-related acid-sensitive K+...
A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1...
A2AR agonist-1 is an agonist of the adenosine A2A receptor and an inhibitor of equilibrative nucleoside transporter 1...
CAS#: Unknown (sodium)
A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors. A-317491 transiently...
A 33 is a potent and selective PDE4B inhibitor.
A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus....
A-350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC).
A-366 is a potent inhibitor of G9a/GLP with IC50 3 nM and > 100-fold selectivity over other methyltransferases and...
A-381393 is a potent and selective agonist of the dopamine D4 receptor.
CAS#: 2089148-72-9 (free base)
A-395 is a potent and selective EED inhibitor. A-395 includes potent binding to EED with Ki = 0.4 nM, inhibits the...
A3 HCl is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.
A 410099.1 HCl
CAS#: 762274-58-8 (HCl)
A 410099.1 is a high affinity XIAP antagonist that is active in vivo.
CAS#: 364042-47-7 (free base)
A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between...
A-419259 trihydrochloride is a second-generation pyrrolo-pyrimidine designed to enhance selectivity towards the Src...
CAS#: 899431-18-6 (HCl)
A-438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen-induced liver injury by inhibiting...
A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K). It reduces eEF-2K...
A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and...
A-582941 exhibits high-affinity binding and agonism at alpha-7 nicotinic acetylcholine receptor , with...
A66 is a potent and highly selective p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity...