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A 582941

CAT#: 558770
CAS#: 848591-90-2

A-582941 exhibits high-affinity binding and agonism at alpha-7 nicotinic acetylcholine receptor , with...

A66

CAT#: 407127
CAS#: 1166227-08-2

A66 is a potent and highly selective p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity...

A-674563

CAT#: 401012
CAS#: 552325-73-2

A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA...

A6770

CAT#: 558989
CAS#: 1331754-16-5

A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.

A-68930 hydrochloride

CAT#: 533327
CAS#: 130465-39-3

A-68930 hydrochloride is a selective D1 dopamine receptor agonist.

A-740003

CAT#: 526702
CAS#: 861393-28-4

A-740003 is a potent and selective P2X7 receptor antagonist. A-740003 has (IC(50) values = 40 nM for human and 18 nM...

A-769662

CAT#: 401018
CAS#: 844499-71-4

A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with an EC50 of 0.8 μM.A-769662...

A-770041

CAT#: 406770
CAS#: 869748-10-7

A-770041 is a potent ans selective LCK inhibitor. Concanavalin A-stimulated IL-2 production in whole blood is...

A77-01

CAT#: 407151
CAS#: 607737-87-1

A 77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25nM.

A-77636 hydrochloride

CAT#: 526416
CAS#: 145307-34-2

A-77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist.

A-779

CAT#: 555596
CAS#: 159432-28-7

A-779 is a peptide antagonist of the Mas receptor, also known as the angiotensin (1-7) (Ang (1-7)) receptor (IC50 =...

A 784168

CAT#: 558771
CAS#: 824982-41-4

A-784168 is a potent and selective antagonist of Vanilloid receptor type 1 (TRPV1).

A-803467

CAT#: 522388
CAS#: 944261-79-4

A-803467 is a potent and selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for...

A-804598

CAT#: 530351
CAS#: 1125758-85-1

A-804598 is a P2X7 selective, competitive antagonist.

A83-01

CAT#: 401002
CAS#: 909910-43-6

A-83-01 is an ALK inhibibitor. It was found that A-83-01 inhibited the transcriptional activity induced by TGF-beta...

A839977

CAT#: 531368
CAS#: 870061-27-1

A839977 is a P2X7R antagonist.

A-867744

CAT#: 526703
CAS#: 1000279-69-5

A-867744 is a type II PAM with good potency and selectivity. A-867744 showed acceptable pharmacokinetic profile...

A 887826

CAT#: 558772
CAS#: 1266212-81-0

A-887826 is Nav1.8 channel blocker of TTX-resistant sodium currents in rat dorsal root ganglion in a voltage...

A-922500

CAT#: 526700
CAS#: 959122-11-3

A-922500 is a potent orally active inhibitor of DGAT-1 activity, inhibiting both human and mouse forms of the enzymes...

A939572

CAT#: 526965
CAS#: 1032229-33-6

A939572 is is a potent and orally bioavailable inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 value of 37nM....

A-943931 HCL

CAT#: 581019
CAS#: 1227675-50-4 (HCL)

A-943931 is Potent and selective H4 antagonist. Potent and selective histamine H4 receptor antagonist (pKi values...

A-966492

CAT#: 406362
CAS#: 934162-61-5

A-966492 is a potent PARP inhibitor, which displayed excellent potency against the PARP-1 enzyme with a K(i) of 1 nM...

A 967079

CAT#: 558773
CAS#: 1170613-55-4

A-967079 is a potent and selective antagonist of Transient Receptor Potential Anykrin 1 (TRPA1) with IC50′s of 67 nM...

AA26-9

CAT#: 555215
CAS#: 1312782-34-5

AA26-9 is a potent and broad-spectrum serine hydrolase inhibitor. AA26-9-inhibited enzymes originated from diverse...

AA41612

CAT#: 574543
CAS#: 433690-62-1

AA41612 is a novel antagonist of melanopsin-mediated phototransduction.