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A-582941 exhibits high-affinity binding and agonism at alpha-7 nicotinic acetylcholine receptor , with...
A66 is a potent and highly selective p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity...
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA...
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.
A-68930 hydrochloride is a selective D1 dopamine receptor agonist.
A-740003 is a potent and selective P2X7 receptor antagonist. A-740003 has (IC(50) values = 40 nM for human and 18 nM...
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with an EC50 of 0.8 μM.A-769662...
A-770041 is a potent ans selective LCK inhibitor. Concanavalin A-stimulated IL-2 production in whole blood is...
A 77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25nM.
A-77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist.
A-779 is a peptide antagonist of the Mas receptor, also known as the angiotensin (1-7) (Ang (1-7)) receptor (IC50 =...
A-784168 is a potent and selective antagonist of Vanilloid receptor type 1 (TRPV1).
A-803467 is a potent and selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for...
A-804598 is a P2X7 selective, competitive antagonist.
A-83-01 is an ALK inhibibitor. It was found that A-83-01 inhibited the transcriptional activity induced by TGF-beta...
A839977 is a P2X7R antagonist.
A-867744 is a type II PAM with good potency and selectivity. A-867744 showed acceptable pharmacokinetic profile...
A-887826 is Nav1.8 channel blocker of TTX-resistant sodium currents in rat dorsal root ganglion in a voltage...
A-922500 is a potent orally active inhibitor of DGAT-1 activity, inhibiting both human and mouse forms of the enzymes...
A939572 is is a potent and orally bioavailable inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 value of 37nM....
CAS#: 1227675-50-4 (HCL)
A-943931 is Potent and selective H4 antagonist. Potent and selective histamine H4 receptor antagonist (pKi values...
A-966492 is a potent PARP inhibitor, which displayed excellent potency against the PARP-1 enzyme with a K(i) of 1 nM...
A-967079 is a potent and selective antagonist of Transient Receptor Potential Anykrin 1 (TRPA1) with IC50′s of 67 nM...
AA26-9 is a potent and broad-spectrum serine hydrolase inhibitor. AA26-9-inhibited enzymes originated from diverse...
AA41612 is a novel antagonist of melanopsin-mediated phototransduction.