Featured Products

A-1331852

CAT#: 406841
CAS#: 1430844-80-6

A-1331852 is a potent BCL-XL-selective inhibitor. BCL-XL is the major antiapoptotic survival protein and may be a...

A1874

CAT#: 573175
CAS#: 2064292-12-0

A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells.

A1899

CAT#: 563499
CAS#: 498577-46-1

A1899 is a potent and selective TASK-1 and TASK-3 antagonist.

A-192621

CAT#: 526692
CAS#: 195529-54-5

A-192621 is an endothelin-B antagonist. A-192621 markedly enhanced MAP, TPR, and mesenteric, and the renal...

A-196

CAT#: 407272
CAS#: Unknown

A-196 is the first potent and selective chemical probe for SUV420H1 and SUV420H2. The in vitro activity of A-196...

A-205804

CAT#: 558769
CAS#: 251992-66-2

A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM...

A22 hydrochloride

CAT#: 555259
CAS#: 22816-60-0 (HCl)

A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant....

A2-32-01

CAT#: 466284
CAS#: 1359752-95-6

A2-32-01 is a HsClpP antagonist.

A2793

CAT#: 556009
CAS#: 88349-90-0

A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TWIK-related acid-sensitive K+...

A286982

CAT#: 531346
CAS#: 280749-17-9

A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1...

A2AR agonist-1

CAT#: 574042
CAS#: 41552-95-8

A2AR agonist-1 is an agonist of the adenosine A2A receptor and an inhibitor of equilibrative nucleoside transporter 1...

A-317491 sodium

CAT#: 526701
CAS#: Unknown (sodium)

A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors. A-317491 transiently...

A 33

CAT#: 584987
CAS#: 915082-52-9

A 33 is a potent and selective PDE4B inhibitor.

A33903

CAT#: 466046
CAS#: 70890-53-8

A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus....

A-350619 hydrochloride

CAT#: 526079
CAS#: 1217201-17-6

A-350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC).

A-366

CAT#: 407285
CAS#: 1527503-11-2

A-366 is a potent inhibitor of G9a/GLP with IC50 3 nM and > 100-fold selectivity over other methyltransferases and...

A-381393

CAT#: 531353
CAS#: 726174-00-1

A-381393 is a potent and selective agonist of the dopamine D4 receptor.

A-395 hydrochloride

CAT#: 407490
CAS#: 2089148-72-9 (free base)

A-395 is a potent and selective EED inhibitor. A-395 includes potent binding to EED with Ki = 0.4 nM, inhibits the...

A3 HCl

CAT#: 527839
CAS#: 78957-85-4

A3 HCl is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.

A 410099.1 HCl

CAT#: 584794
CAS#: 762274-58-8 (HCl)

A 410099.1 is a high affinity XIAP antagonist that is active in vivo.

A-419259

CAT#: 555204
CAS#: 364042-47-7 (free base)

A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between...

A-419259 trihydrochloride

CAT#: 574542
CAS#: 1435934-25-0

A-419259 trihydrochloride is a second-generation pyrrolo-pyrimidine designed to enhance selectivity towards the Src...

A-438079 HCl

CAT#: 526699
CAS#: 899431-18-6 (HCl)

A-438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen-induced liver injury by inhibiting...

A-484954

CAT#: 573979
CAS#: 142557-61-7

A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K). It reduces eEF-2K...

A-485

CAT#: 555116
CAS#: 1889279-16-6

A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and...