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A-350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC).
A-366 is a potent inhibitor of G9a/GLP with IC50 3 nM and > 100-fold selectivity over other methyltransferases and...
A-381393 is a potent and selective agonist of the dopamine D4 receptor.
CAS#: 2089148-72-9 (free base)
A-395 is a potent and selective EED inhibitor. A-395 includes potent binding to EED with Ki = 0.4 nM, inhibits the...
A3 HCl is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.
A 410099.1 HCl
CAS#: 762274-58-8 (HCl)
A 410099.1 is a high affinity XIAP antagonist that is active in vivo.
CAS#: 364042-47-7 (free base)
A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between...
A-419259 trihydrochloride is a second-generation pyrrolo-pyrimidine designed to enhance selectivity towards the Src...
CAS#: 899431-18-6 (HCl)
A-438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen-induced liver injury by inhibiting...
A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K). It reduces eEF-2K...
A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and...
A-582941 exhibits high-affinity binding and agonism at alpha-7 nicotinic acetylcholine receptor , with...
A66 is a potent and highly selective p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity...
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA...
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.
A-68930 hydrochloride is a selective D1 dopamine receptor agonist.
A-740003 is a potent and selective P2X7 receptor antagonist. A-740003 has (IC(50) values = 40 nM for human and 18 nM...
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with an EC50 of 0.8 μM.A-769662...
A-770041 is a potent ans selective LCK inhibitor. Concanavalin A-stimulated IL-2 production in whole blood is...
A 77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25nM.
A-77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist.
A-779 is a peptide antagonist of the Mas receptor, also known as the angiotensin (1-7) (Ang (1-7)) receptor (IC50 =...
A-784168 is a potent and selective antagonist of Vanilloid receptor type 1 (TRPV1).
A-803467 is a potent and selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for...
A-804598 is a P2X7 selective, competitive antagonist.