WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 525036
Description: Famphur is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 22.214.171.124 (acetylcholinesterase) inhibitor, an agrochemical, and an anthelminthic drug. Use of famphur as an insecticide is restricted.
MedKoo Cat#: 525036
Chemical Formula: C10H16NO5PS2
Exact Mass: 325.02075
Molecular Weight: 325.34
Elemental Analysis: C, 36.92; H, 4.96; N, 4.31; O, 24.59; P, 9.52; S, 19.71
Synonym: Famphur; FAMOPHOS; Famofos; Famphos; Warbexol; Famfur; Varbex; Warbex; Dovip.
IUPAC/Chemical Name: O,O-Dimethyl O-(p-(dimethylsulfamoyl)phenyl) phosphorothioate
InChi Key: JISACBWYRJHSMG-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H16NO5PS2/c1-11(2)19(12,13)10-7-5-9(6-8-10)16-17(18,14-3)15-4/h5-8H,1-4H3
SMILES Code: P(=S)(Oc1ccc(cc1)S(=O)(=O)N(C)C)(OC)OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in water (partly), chloroform, dichloromethane, DMSO, acetone, and toluene
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 325.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Braselton WE, Johnson JL, Carlson MP, Schneider NR. Gas chromatography/mass spectrometry identification and quantification of isazophos in a famphur pour-on and in bovine tissues after a toxic exposure. J Vet Diagn Invest. 2000 Jan;12(1):15-20. PubMed PMID: 10690770.
2: Campbell JB, Knapp FW, Loomis EC, Boxler DJ, Herald F, Dunning LL. Efficacy of levamisole/famphur paste for control of cattle grubs (Diptera: Oestridae) and gastrointestinal worms (Nematoda: Trichostrongylidae). J Econ Entomol. 1987 Oct;80(5):1028-30. PubMed PMID: 3693663.
3: Franson JC, Kolbe EJ, Carpenter JW. Famphur toxicosis in a bald eagle. J Wildl Dis. 1985 Jul;21(3):318-20. PubMed PMID: 4032636.
4: Watson K, Black WD. Whole blood cholinesterase activity in calves after topical treatment with famphur. Can Vet J. 1981 Jun;22(6):179-81. PubMed PMID: 7284948; PubMed Central PMCID: PMC1789936.
5: Randell WF, Bradley RE. Effects of injectable famphur on young Brahman and Angus cattle. Am J Vet Res. 1980 Sep;41(9):1423-6. PubMed PMID: 7447135.
6: Teel PD, Hair JA, Stratton LG. Laboratory evaluation of a sustained-release famphur bolus against Gulf Coast and lone star ticks feeding on Hereford heifers. J Econ Entomol. 1979 Apr;72(2):230-3. PubMed PMID: 536488.