ZM 260384

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526585

CAS#: 161229-62-5

Description: ZM 260384 is a potassium channel opener.

Chemical Structure

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ZM 260384
CAS# 161229-62-5
Instruction

Theoretical Analysis

MedKoo Cat#: 526585
Name: ZM 260384
CAS#: 161229-62-5
Chemical Formula: C15H11F4N3O4
Exact Mass: 373.07
Molecular Weight: 373.264
Elemental Analysis: C, 48.27; H, 2.97; F, 20.36; N, 11.26; O, 17.14

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ZM 260384; ZM-260384; ZM260384

IUPAC/Chemical Name: 2-(2,2-bis(difluoromethyl)-6-nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)pyridine 1-oxide

InChi Key: LIKAVDUPUINJPY-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H11F4N3O4/c16-13(17)15(14(18)19)8-20(12-3-1-2-6-21(12)23)10-7-9(22(24)25)4-5-11(10)26-15/h1-7,13-14H,8H2

SMILES Code: [O-][N+]1=CC=CC=C1N2CC(C(F)F)(C(F)F)OC3=CC=C([N+]([O-])=O)C=C23

Appearance: White to off-white solid powder.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 373.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shaw-Reid CA, Feuston B, Munshi V, Getty K, Krueger J, Hazuda DJ, Parniak MA, Miller MD, Lewis D. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities. Biochemistry. 2005 Feb 8;44(5):1595-606. PubMed PMID: 15683243.

2: Wickenden Ad, Brooks R, Kelly E, Russell K, Kumar P, Poucher SM. Effect of the potassium channel opener ZM260384 on skeletal muscle function during restricted blood flow in the anaesthetized cat. Exp Physiol. 1997 Jan;82(1):85-98. PubMed PMID: 9023508.