WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526577

CAS#: 7361-61-7 (free base)

Description: Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats.

Chemical Structure

CAS# 7361-61-7 (free base)

Theoretical Analysis

MedKoo Cat#: 526577
Name: Xylazine
CAS#: 7361-61-7 (free base)
Chemical Formula: C12H16N2S
Exact Mass: 220.10
Molecular Weight: 220.334
Elemental Analysis: C, 65.42; H, 7.32; N, 12.71; S, 14.55

Price and Availability

Size Price Availability Quantity
1g USD 150
2g USD 250
5g USD 450
10g USD 650
25g USD 950
50g USD 1650
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Related CAS #: 23076-35-9 (HCl)   7361-61-7 (free base)    

Synonym: Xylazine; BAY-VA 1470; Anased; BAY 1470; BAY1470; BAY-1470; Primazine; Rometar; Sedomin; WH 7286; Xilazina

IUPAC/Chemical Name: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine


InChi Code: InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)

SMILES Code: 2,6-Xylidine, N-(5,6-dihydro-4H-1,3-thiazinyl)-

Appearance: White to off-white crystalline powder.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 220.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Ruiz-Colón K, Chavez-Arias C, Díaz-Alcalá JE, Martínez MA. Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. Forensic Sci Int. 2014 Jul;240:1-8. doi: 10.1016/j.forsciint.2014.03.015. Epub 2014 Mar 26. Review. PubMed PMID: 24769343.

2: Mittleman RE, Hearn WL, Hime GW. Xylazine toxicity--literature review and report of two cases. J Forensic Sci. 1998 Mar;43(2):400-2. Review. PubMed PMID: 9544551.

3: Fyffe JJ. Effects of xylazine on humans: a review. Aust Vet J. 1994 Sep;71(9):294-5. Review. PubMed PMID: 7818438.

4: Schmidt-Oechtering GU, Alef M, Röcken M. [Anesthesia of horses with xylazine and ketamine. 2. Anesthesia in adult horses]. Tierarztl Prax. 1990 Feb;18(1):47-52. Review. German. PubMed PMID: 2183391.

5: Greene SA, Thurmon JC. Xylazine--a review of its pharmacology and use in veterinary medicine. J Vet Pharmacol Ther. 1988 Dec;11(4):295-313. Review. PubMed PMID: 3062194.

6: Capraro AJ, Wiley JF 2nd, Tucker JR. Severe intoxication from xylazine inhalation. Pediatr Emerg Care. 2001 Dec;17(6):447-8. Review. PubMed PMID: 11753193.

7: Hoffmann U, Meister CM, Golle K, Zschiesche M. Severe intoxication with the veterinary tranquilizer xylazine in humans. J Anal Toxicol. 2001 May-Jun;25(4):245-9. Review. PubMed PMID: 11386637.

8: Chamberlain PL, Brynes SD. The regulatory status of xylazine for use in food-producing animals in the United States. J Vet Pharmacol Ther. 1998 Aug;21(4):322-9. Review. PubMed PMID: 9731956.

9: Schmidt-Oechtering GU, Becker K. [Old and new alpha 2-adrenoceptor agonists. 1. Xylazine and medetomidine]. Tierarztl Prax. 1992 Oct;20(5):447-58. Review. German. PubMed PMID: 1359676.

10: Gallanosa AG, Spyker DA, Shipe JR, Morris DL. Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants. Clin Toxicol. 1981 Jun;18(6):663-78. Review. PubMed PMID: 6115734.

11: Holmes AM, Clark WT. Xylazine for sedation of horses. N Z Vet J. 1977 Jun;25(6):159-61. Review. PubMed PMID: 351482.