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MedKoo CAT#: 526557

CAS#: 80456-55-9

Description: Vibunazole is an antifungal agent

Price and Availability

Size Price Shipping out time Quantity
10mg USD 220 2 Weeks
20mg USD 410 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-02-27. Prices are subject to change without notice.

Vibunazole, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide).

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 526557
Name: Vibunazole
CAS#: 80456-55-9
Chemical Formula: C15H20ClN3O2
Exact Mass: 309.1244
Molecular Weight: 309.794
Elemental Analysis: C, 58.16; H, 6.51; Cl, 11.44; N, 13.56; O, 10.33

Synonym: Bay N 7133; BayN 7133; Bay-N 7133; Vibunazole

IUPAC/Chemical Name: 2-((1H-1,2,4-triazol-1-yl)methyl)-1-(4-chlorophenoxy)-3,3-dimethylbutan-2-ol


InChi Code: InChI=1S/C15H20ClN3O2/c1-14(2,3)15(20,8-19-11-17-10-18-19)9-21-13-6-4-12(16)5-7-13/h4-7,10-11,20H,8-9H2,1-3H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


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2: Lefler E, Stevens DA. New azole compounds: vibunazole (Bay n7133) and Bay L9139, compared with ketoconazole in the therapy of systemic candidosis and in pharmacokinetic studies, in mice. J Antimicrob Chemother. 1985 Jan;15(1):69-75. PubMed PMID: 3972759.

3: Ritter W, Plempel M. Pharmacokinetics of the oral triazole antimycotic vibunazole in animals. J Antimicrob Chemother. 1984 Sep;14(3):243-52. PubMed PMID: 6490569.

4: Odds FC, Webster CE, Abbott AB. Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents. J Antimicrob Chemother. 1984 Aug;14(2):105-14. PubMed PMID: 6094418.

5: Ritter W, Holmwood G, Ahr HJ, Detzer K, Kraatz U, Plempel M, Scherling D, Siefert HM. Vibunazole and its enantiomers. Synthesis, antifungal activity, and pharmacokinetics. Ann N Y Acad Sci. 1988;544:74-85. PubMed PMID: 3063187.

6: Schaude M, Meingassner JG. A diffusion chamber technique for testing of antifungal drugs against Sporothrix schenckii in vivo. J Med Vet Mycol. 1986 Aug;24(4):297-304. PubMed PMID: 3018212.

7: Perfect JR, Durack DT. Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits. J Antimicrob Chemother. 1985 Jul;16(1):81-6. PubMed PMID: 2995303.

8: Hiratani T, Yamaguchi H. [Cross-resistance of Candida albicans to several different families of antifungals with ergosterol biosynthesis-inhibiting activity]. Jpn J Antibiot. 1994 Feb;47(2):125-8. Japanese. PubMed PMID: 8151906.

9: Hughes CE, Beggs WH. Action of fluconazole (UK-49,858) in relation to other systemic antifungal azoles. J Antimicrob Chemother. 1987 Feb;19(2):171-4. PubMed PMID: 3032882.

10: Okeke CN, Gugnani HC. In vitro sensitivity of environmental isolates of pathogenic dematiaceous fungi to azole compounds and a phenylpropyl-morpholine derivative. Mycopathologia. 1987 Sep;99(3):175-81. PubMed PMID: 3657909.

11: Fromtling RA, Abruzzo GK, Bulmer GS. Cryptococcus neoformans: comparisons of in vitro antifungal susceptibilities of serotypes AD and BC. Mycopathologia. 1986 Apr;94(1):27-30. PubMed PMID: 3014339.

12: Meunier F. Serum fungistatic and fungicidal activity in volunteers receiving antifungal agents. Eur J Clin Microbiol. 1986 Feb;5(1):103-9. PubMed PMID: 3516681.

13: Beggs WH, Hughes CE. Irrelevance of growth phase with respect to the Bay n 7133 and ICI 153,066 susceptibilities of Candida albicans. Diagn Microbiol Infect Dis. 1986 Jan;4(1):83-6. PubMed PMID: 3510807.

14: Hoeprich PD, Merry JM. Activity of BAY n 7133 and BAY 1 9139 in vitro and in experimental murine coccidioidomycosis. Eur J Clin Microbiol. 1985 Aug;4(4):400-3. PubMed PMID: 4043057.

15: Ackerbauer H, Meingassner JG, Mieth H. [Experimental renal infection with Aspergillus fumigatus in mice: a chemotherapeutic model of an organic mycosis]. Mykosen. 1985 May;28(5):244-50. German. PubMed PMID: 2989682.

16: Lefler E, Brummer E, Perlman AM, Stevens DA. Activities of the modified polyene N-D-ornithyl amphotericin methyl ester and the azoles ICI 153066, Bay n 7133, and Bay l 9139 compared with those of amphotericin B and ketoconazole in the therapy of experimental blastomycosis. Antimicrob Agents Chemother. 1985 Mar;27(3):363-6. PubMed PMID: 3994350; PubMed Central PMCID: PMC176278.

17: Lefler E, Brummer E, McEwen JG, Hoyos GL, Restrepo A, Stevens DA. Study of current and new drugs in a murine model of acute paracoccidioidomycosis. Am J Trop Med Hyg. 1985 Jan;34(1):134-40. PubMed PMID: 3970306.

18: Espinel-Ingroff A, Shadomy S, Gebhart RJ. In vitro studies with R 51,211 (itraconazole). Antimicrob Agents Chemother. 1984 Jul;26(1):5-9. PubMed PMID: 6089654; PubMed Central PMCID: PMC179904.

19: Fromtling RA, Yu HP, Shadomy S. In vitro antifungal activities of Bay n 7133 and Bay L 9139, two new orally absorbed antifungal imidazole derivatives, against pathogenic yeasts. Mycopathologia. 1984 Apr 30;86(1):45-50. PubMed PMID: 6330557.

20: Nusch W, Plempel M. [Microbiological determination of the oral antifungal agent Bay N 7133 and ketoconazole in cervical and vaginal secretion of patients]. Mykosen. 1983 Dec;26(12):600-4. German. PubMed PMID: 6319990.