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MedKoo CAT#: 526559

CAS#: 4880-88-0

Description: Vinburnine, also known as Eburnamonine, is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine.

Price and Availability

Size Price Shipping out time Quantity
25mg USD 250 2 Weeks
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 1850 2 Weeks
1g USD 2450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-04-08. Prices are subject to change without notice.

Vinburnine, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide).

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 526559
Name: Vinburnine
CAS#: 4880-88-0
Chemical Formula: C19H22N2O
Exact Mass: 294.1732
Molecular Weight: 294.398
Elemental Analysis: C, 77.52; H, 7.53; N, 9.52; O, 5.43

Synonym: CH846; CH-846; CH 846; Vinburnine; Eburnal; Eburnamonine

IUPAC/Chemical Name: (13aR)-13a-ethyl-2,3,5,6,13,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-12(41H)-one


InChi Code: InChI=1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18?,19-/m1/s1

SMILES Code: O=C1N2C3=C(C4=C2C=CC=C4)CCN5C3[C@@](CCC5)(CC)C1

Technical Data

White to off-white solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Louajri A, Harraga S, Toubin G, Kantelip JP. Red blood cell metabolism and hemoglobin oxygen affinity. Effect of vinburnine on normobaric hypoxic rats. Biol Pharm Bull. 1999 Aug;22(8):773-4. PubMed PMID: 10480311.

2: Schena D, Menegazzi S, Barba A. Bullous fixed drug eruption induced by vinburnine. Contact Dermatitis. 1992 Sep;27(3):187. PubMed PMID: 1451466.

3: Acciavatti A, Domini L, Galigani C, Saletti M, Guideri F, Auteri A, Di Perri T. [The effects of vinburnine on the blood rheology parameters and on the oxyhemoglobin dissociation curve and 2,3-diphosphoglycerate. In vitro research]. Recenti Prog Med. 1990 Nov;81(11):710-5. Italian. PubMed PMID: 2287807.

4: Drago F, Grassi M, Valerio C, Spadaro F, D'Agata V, Lauria N. Effects of vinburnine on experimental models of learning and memory impairments. Pharmacol Biochem Behav. 1990 Sep;37(1):53-7. PubMed PMID: 2263666.

5: Sado PA, Gibassier D, Leverge R. [The effect of modification of excipients for the bioavailability of vinburnine]. J Pharm Belg. 1989 May-Jun;44(3):221-9. French. PubMed PMID: 2795425.

6: Sado PA, Gibassier D, Leverge R. [The oral liquid form of vinburnine: biopharmaceutics]. J Pharm Belg. 1989 Jan-Feb;44(1):50-9. French. PubMed PMID: 2724048.

7: Barzaghi F, Dragonetti M, Formento ML, Gueniau C, Nencioni A, Mantegazza P. A comparison of some of the pharmacological properties of the new eburnamenine derivative vindeburnol with those of vincamine, vinburnine, dihydroergotoxine mesilate and nicergoline. Arzneimittelforschung. 1986 Oct;36(10):1442-8. PubMed PMID: 3814205.

8: Maksay G, Bíró T, Kiss B. Vinburnine decelerates [3H]N-methylscopolamine binding to recombinant human muscarinic M1-M4 acetylcholine receptors. Eur J Pharmacol. 2004 Jan 12;483(2-3):229-32. PubMed PMID: 14729111.

9: Chauveau E, Prignet JM, Carloz E, Duval JL, Gilles B. [Lymphocytic colitis likely attributable to use of vinburnine (Cervoxan)]. Gastroenterol Clin Biol. 1998 Mar;22(3):362. French. PubMed PMID: 9762227.

10: Domini L, Acciavatti A, Galigani C, Saletti M, De Franco V, Pecchi S, Auteri A, Di Perri T. [The effects of the acute administration of vinburnine on blood rheology, oxygen transport and regional circulation under normal conditions and in hypoxemia. In vivo research]. Recenti Prog Med. 1990 Nov;81(11):716-23. Italian. PubMed PMID: 2287808.

11: Bentue-Ferrer D, Philouze V, Pape D, Reymann JM, Allain H, Van den Driessche J. Comparative evaluation of scavenger properties of exifone, piracetam and vinburnine. Fundam Clin Pharmacol. 1989;3(4):323-8. PubMed PMID: 2807130.

12: Sado PA, Gibassier D, Leverge R. [Simultaneous determination of vinburnine and 6-hydroxyvinburnine in human plasma by high-performance liquid chromatography]. J Chromatogr. 1988 Dec 29;434(1):157-67. French. PubMed PMID: 3243809.

13: Giordano F, Pavan M, La Manna A, Bettinetti GP, Pavesi L, Bovis G. Complexation behavior of vinburnine with beta and gamma cyclodextrins in aqueous solution and in the solid state. Farmaco Prat. 1988 Nov;43(11):345-55. PubMed PMID: 3243350.

14: Sado PA, Gibassier D, Leverge R. [Bioavailability of vinburnine in man: importance of combination with ascorbic acid]. J Pharm Belg. 1986 Jan-Feb;41(1):17-28. French. PubMed PMID: 3701564.

15: Sado PA, Gibassier D, Le Verge R, Acerbi D, Schiantarelli P. [Relative bioavailability of vinburnine in man (microgranules/gels)]. J Pharm Belg. 1985 Sep-Oct;40(5):308-22. French. PubMed PMID: 4087124.