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MedKoo CAT#: 524407

CAS#: 29462-18-8

Description: Bentazepam is a thienodiazepine which is a benzodiazepine analog. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Peak plasma rates are achieved in around 2,5 hours after oral administration.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 160 2 weeks
100mg USD 625 2 weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-10. Prices are subject to change without notice.

Bentazepam purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 524407
Name: Bentazepam
CAS#: 29462-18-8
Chemical Formula: C17H16N2OS
Exact Mass: 296.09833
Molecular Weight: 296.39
Elemental Analysis: C, 68.89; H, 5.44; N, 9.45; O, 5.40; S, 10.82

Synonym: Bentazepam; Thiadipone; Tiadipone; Bentazepam [USAN:INN]; CI-718; Knoll brand of bentazepam; QM 6008; QM-6008; Thiadipone; Tiadipona;

IUPAC/Chemical Name: 1,3,6,7,8,9-Hexahydro-5-phenyl-2H-(1)benzothieno(2,3-e)-1,4-diazepin-2-one


InChi Code: InChI=1S/C17H16N2OS/c20-14-10-18-16(11-6-2-1-3-7-11)15-12-8-4-5-9-13(12)21-17(15)19-14/h1-3,6-7H,4-5,8-10H2,(H,19,20)

SMILES Code: c1ccc(cc1)C2=NCC(=O)Nc3c2c4c(s3)CCCC4

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Andrade RJ, López-Torres E, Lucena MI, Fernández Mdel C. [Acute hepatitis due to bentazepam]. Med Clin (Barc). 2003 May 10;120(17):678-9. Spanish. PubMed PMID: 12747823.

2: Andrade RJ, Lucena MI, Aguilar J, Lazo MD, Camargo R, Moreno P, García-Escaño MD, Marquez A, Alcántara R, Alcáin G. Chronic liver injury related to use of bentazepam: an unusual instance of benzodiazepine hepatotoxicity. Dig Dis Sci. 2000 Jul;45(7):1400-4. PubMed PMID: 10961721.

3: de-la-Serna C, Gil-Grande LA, Sanromán AL, Gonzalez M, Ruiz-del-Arbol L, Garcia Plaza A. Bentazepam-induced hepatic bridging necrosis. J Clin Gastroenterol. 1997 Dec;25(4):710-1. PubMed PMID: 9451703.

4: Andrade RJ, Lucena MI, Alcantara R, Fraile JM. Bentazepam-associated chronic liver disease. Lancet. 1994 Apr 2;343(8901):860. PubMed PMID: 7908109.

5: Colino CI, Lastra CF, López FG, Ledesma A, Mariño EL. Open-loop feedback control of serum bentazepam concentrations and Bayesian estimation in multiple dosage regimens in patients. Int J Clin Pharmacol Ther Toxicol. 1991 Nov;29(11):457-62. PubMed PMID: 1800395.

6: Honorato J, Rubio A, Tristán C, Otero FJ, Garrido J. [A pharmacovigilance study with bentazepam in a sample of 1046 psychiatric outpatients]. Rev Med Univ Navarra. 1990 Apr-Jun;34(2):80-8. Spanish. PubMed PMID: 1983365.

7: Fernandez Lastra C, Gonzalez Lopez F, Dominguez-Gil A, Mariño EL. Discrimination of kinetic models in heteroscedastic parametric estimation of bentazepam following multiple dosing. Int J Clin Pharmacol Ther Toxicol. 1988 Jul;26(7):335-8. PubMed PMID: 3209281.

8: Mariño EL, Fernandez Lastra C, Gonzalez Lopez F, Martin Rey A, Dominguez-Gil A, Garcia-Santalla JL, Llorca G, Izquiexdo JA, Ledesma-Jimeno A. Simulation of plasma bentazepam levels in multiple dosage regimens from parameters established by non-linear regression and bayesian estimation. Int J Clin Pharmacol Ther Toxicol. 1987 Dec;25(12):664-9. PubMed PMID: 2893777.

9: Mariño EL, Fernandez Lastra C, Gonzalez Lopez F, Dominguez-Gil A, Garcia Santalla JL, Vorca G, Izquierdo JA, Ledesma-Jimeno A. Parametrization by non-linear regression and bayesian estimation of bentazepam in a multiple dosage regimen in humans. Int J Clin Pharmacol Ther Toxicol. 1987 Nov;25(11):627-32. PubMed PMID: 3429066.

10: Lopez FG, Mariño EL, Dominguez-Gil A. Determination of bentazepam in plasma by high-performance liquid chromatography. J Pharm Biomed Anal. 1987;5(6):553-8. PubMed PMID: 16867478.