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MedKoo CAT#: 524369

CAS#: 127294-70-6

Description: Balofloxacin is a fluoroquinolone antibiotic. Balofloxacin has shown potent bactericidal activity & inhibited the supercoiling activity of DNA gyrase of S. aureus, E. coli, & P aeruginosa. It is sold under the brand name Q-Roxin in Korea.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 200 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-19. Prices are subject to change without notice.

Balofloxacin purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 524369
Name: Balofloxacin
CAS#: 127294-70-6
Chemical Formula: C20H24FN3O4
Exact Mass: 389.17508
Molecular Weight: 389.42
Elemental Analysis: C, 61.68; H, 6.21; F, 4.88; N, 10.79; O, 16.43

Synonym: Balofloxacin; Balofloxacin [INN]; Q 35; UNII-Q022B63JPM; Q-35; Q35;

IUPAC/Chemical Name: (+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-(methylamino)piperidino)-4-oxo-3-quinolinecarboxylic acid


InChi Code: InChI=1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27)

SMILES Code: CNC1CCCN(C1)c2c(cc3c(c2OC)n(cc(c3=O)C(=O)O)C4CC4)F

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Chen XH, Zhang BW, Li H, Peng XX. Myo-inositol improves the host's ability to eliminate balofloxacin-resistant Escherichia coli. Sci Rep. 2015 Jun 1;5:10720. doi: 10.1038/srep10720. PubMed PMID: 26030712.

2: Ma X, Yan J, Wang Q, Wu D, Li H. Spectroscopy study and co-administration effect on the interaction of mycophenolic acid and human serum albumin. Int J Biol Macromol. 2015;77:280-6. doi: 10.1016/j.ijbiomac.2015.03.052. Epub 2015 Apr 1. PubMed PMID: 25841376.

3: Jiang H, Han S, Guo C, Liu T, Wu X. In vitro and in vivo effectiveness evaluation of balofloxacin in experimental Staphylococcus aureus keratitis. J Ocul Pharmacol Ther. 2014 Aug;30(6):482-8. doi: 10.1089/jop.2013.0178. Epub 2014 May 14. PubMed PMID: 24828089.

4: Li H, Pan JY, Liu XJ, Gao JX, Wu HK, Wang C, Peng XX. Alterations of protein complexes and pathways in genetic information flow and response to stimulus contribute to Escherichia coli resistance to balofloxacin. Mol Biosyst. 2012 Sep;8(9):2303-11. Epub 2012 Jun 22. PubMed PMID: 22729160.

5: Li P, Liu X, Li H, Peng XX. Downregulation of Na(+)-NQR complex is essential for Vibrio alginolyticus in resistance to balofloxacin. J Proteomics. 2012 May 17;75(9):2638-48. doi: 10.1016/j.jprot.2012.03.006. Epub 2012 Mar 17. PubMed PMID: 22465713.

6: Feng LS, Liu ML, Wang B, Chai Y, Hao XQ, Meng S, Guo HY. Synthesis and in vitro antimycobacterial activity of balofloxacin ethylene isatin derivatives. Eur J Med Chem. 2010 Aug;45(8):3407-12. doi: 10.1016/j.ejmech.2010.04.027. Epub 2010 May 20. PubMed PMID: 20493593.