WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 318902

CAS#: 396-01-0

Description: Triamterene is a potassium-sparing diuretic used in combination with thiazide diuretics for the treatment of hypertension and edema. Triamterene directly blocks the epithelial sodium channel (ENaC) on the lumen side of the kidney collecting tubule. Other diuretics cause a decrease in the sodium concentration of the forming urine due to the entry of sodium into the cell via the ENaC, and the concomitant exit of potassium from the principal cell into the forming urine. Blocking ENaC prevents this from happening. Amiloride works in the same way. Sodium channel blockers directly inhibit the entry of sodium into the sodium channels.

Chemical Structure

CAS# 396-01-0

Theoretical Analysis

MedKoo Cat#: 318902
Name: Triamterene
CAS#: 396-01-0
Chemical Formula: C12H11N7
Exact Mass: 253.11
Molecular Weight: 253.269
Elemental Analysis: C, 56.91; H, 4.38; N, 38.71

Price and Availability

Size Price Availability Quantity
5g USD 250
25g USD 600 2 Weeks
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Synonym: BRN 0266723; BRN0266723; BRN-0266723; Triamterene; Diucelpin; Diurene

IUPAC/Chemical Name: 6-phenylpteridine-2,4,7-triamine


InChi Code: InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)

SMILES Code: NC1=NC(N)=C2N=C(C3=CC=CC=C3)C(N)=NC2=N1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 253.269000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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