WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 319901
Description: Viquidacin, also known as NXL-101, is an oral/iv antibiotic targeting Gram positive bacteria such as MRSA. In 2008 Novexel announced that it has discontinued development of viquidacin (NXL 101). The decision was based on QT interval prolongation, which was observed in healthy.
MedKoo Cat#: 319901
Chemical Formula: C25H29FN2O4S2
Exact Mass: 504.1553
Molecular Weight: 504.6354
Elemental Analysis: C, 59.50; H, 5.79; F, 3.76; N, 5.55; O, 12.68; S, 12.71
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: NXL-101, NXL 101, NXL101, Viquidacin
IUPAC/Chemical Name: (3R,4R)-4-((3S)-3-(3-Fluoro-6-methoxyquinolin-4-yl)-3-hydroxypropyl)-1-(2-((thiophen-2-yl)sulfanyl)ethyl)piperidine-3-carboxylic acid
InChi Key: USGHRRVFKSLEJT-WVBUVRCRSA-N
InChi Code: InChI=1S/C25H29FN2O4S2/c1-32-17-5-6-21-18(13-17)24(20(26)14-27-21)22(29)7-4-16-8-9-28(15-19(16)25(30)31)10-12-34-23-3-2-11-33-23/h2-3,5-6,11,13-14,16,19,22,29H,4,7-10,12,15H2,1H3,(H,30,31)/t16-,19+,22+/m1/s1
SMILES Code: O=C([C@H]1CN(CCSC2=CC=CS2)CC[C@H]1CC[C@@H](C3=C(F)C=NC4=CC=C(OC)C=C34)O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 504.6354 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|