Viquidacin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319901

CAS#: 904302-98-3

Description: Viquidacin, also known as NXL-101, is an oral/iv antibiotic targeting Gram positive bacteria such as MRSA. In 2008 Novexel announced that it has discontinued development of viquidacin (NXL 101). The decision was based on QT interval prolongation, which was observed in healthy.


Chemical Structure

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Viquidacin
CAS# 904302-98-3

Theoretical Analysis

MedKoo Cat#: 319901
Name: Viquidacin
CAS#: 904302-98-3
Chemical Formula: C25H29FN2O4S2
Exact Mass: 504.1553
Molecular Weight: 504.6354
Elemental Analysis: C, 59.50; H, 5.79; F, 3.76; N, 5.55; O, 12.68; S, 12.71

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: NXL-101, NXL 101, NXL101, Viquidacin

IUPAC/Chemical Name: (3R,4R)-4-((3S)-3-(3-Fluoro-6-methoxyquinolin-4-yl)-3-hydroxypropyl)-1-(2-((thiophen-2-yl)sulfanyl)ethyl)piperidine-3-carboxylic acid

InChi Key: USGHRRVFKSLEJT-WVBUVRCRSA-N

InChi Code: InChI=1S/C25H29FN2O4S2/c1-32-17-5-6-21-18(13-17)24(20(26)14-27-21)22(29)7-4-16-8-9-28(15-19(16)25(30)31)10-12-34-23-3-2-11-33-23/h2-3,5-6,11,13-14,16,19,22,29H,4,7-10,12,15H2,1H3,(H,30,31)/t16-,19+,22+/m1/s1

SMILES Code: O=C([C@H]1CN(CCSC2=CC=CS2)CC[C@H]1CC[C@@H](C3=C(F)C=NC4=CC=C(OC)C=C34)O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 504.6354 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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