Viquidacin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319901

CAS#: 904302-98-3

Description: Viquidacin, also known as NXL-101, is an oral/iv antibiotic targeting Gram positive bacteria such as MRSA. In 2008 Novexel announced that it has discontinued development of viquidacin (NXL 101). The decision was based on QT interval prolongation, which was observed in healthy.


Price and Availability

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Viquidacin is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international). Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 319901
Name: Viquidacin
CAS#: 904302-98-3
Chemical Formula: C25H29FN2O4S2
Exact Mass: 504.1553
Molecular Weight: 504.6354
Elemental Analysis: C, 59.50; H, 5.79; F, 3.76; N, 5.55; O, 12.68; S, 12.71


Synonym: NXL-101, NXL 101, NXL101, Viquidacin

IUPAC/Chemical Name: (3R,4R)-4-((3S)-3-(3-Fluoro-6-methoxyquinolin-4-yl)-3-hydroxypropyl)-1-(2-((thiophen-2-yl)sulfanyl)ethyl)piperidine-3-carboxylic acid

InChi Key: USGHRRVFKSLEJT-WVBUVRCRSA-N

InChi Code: InChI=1S/C25H29FN2O4S2/c1-32-17-5-6-21-18(13-17)24(20(26)14-27-21)22(29)7-4-16-8-9-28(15-19(16)25(30)31)10-12-34-23-3-2-11-33-23/h2-3,5-6,11,13-14,16,19,22,29H,4,7-10,12,15H2,1H3,(H,30,31)/t16-,19+,22+/m1/s1

SMILES Code: O=C([C@H]1CN(CCSC2=CC=CS2)CC[C@H]1CC[C@@H](C3=C(F)C=NC4=CC=C(OC)C=C34)O)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490