Balapiravir
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MedKoo CAT#: 319850

CAS#: 690270-29-2 (free base)

Description: Balapiravir, also known as R1626 and RO4588161, is a polymerase inhibitor and a tri-isobutyl ester prodrug of R1479, was developed to increase bioavailability and improve antiviral activity.


Chemical Structure

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Balapiravir
CAS# 690270-29-2 (free base)

Theoretical Analysis

MedKoo Cat#: 319850
Name: Balapiravir
CAS#: 690270-29-2 (free base)
Chemical Formula: C21H30N6O8
Exact Mass: 494.21
Molecular Weight: 494.505
Elemental Analysis: C, 51.01; H, 6.12; N, 17.00; O, 25.88

Price and Availability

Size Price Availability Quantity
5mg USD 450 2 Weeks
10mg USD 750 2 Weeks
50mg USD 2250 2 Weeks
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Related CAS #: 690270-29-2 (free base)   690270-65-6 (HCl)    

Synonym: R1626; R-1626; R 1626; RO4588161; RO-4588161; RO 4588161; Balapiravir.

IUPAC/Chemical Name: (2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-azido-2-((isobutyryloxy)methyl)tetrahydrofuran-3,4-diyl bis(2-methylpropanoate)

InChi Key: VKXWOLCNTHXCLF-DXEZIKHYSA-N

InChi Code: InChI=1S/C21H30N6O8/c1-10(2)17(28)32-9-21(25-26-23)15(34-19(30)12(5)6)14(33-18(29)11(3)4)16(35-21)27-8-7-13(22)24-20(27)31/h7-8,10-12,14-16H,9H2,1-6H3,(H2,22,24,31)/t14-,15+,16-,21-/m1/s1

SMILES Code: CC(C(O[C@H]([C@@H]([C@]1(COC(C(C)C)=O)N=[N+]=[N-])OC(C(C)C)=O)[C@@H](O1)N(C=CC(N)=N2)C2=O)=O)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
SDMSO 100.0 202.22

Preparing Stock Solutions

The following data is based on the product molecular weight 494.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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