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MedKoo CAT#: 319785

CAS#: 929622-08-2 (free base)

Description: Bavisant, also known as JNJ-31001074, is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. Histamine H3 receptors reside on non-histamine neurons and regulate other neurotransmitters (e.g. acetylcholine, noradrenaline [norepinephrine]) suggesting that H3 antagonists have the potential to improve attention and impulsivity. Research indicates that H3 receptor antagonists due to their novel mechanism of action may have a unique treatment effect offering an important alternative for the treatment of ADHD.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-09-27. Prices are subject to change without notice.

Bavisant, purity > 98%, is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 319785
Name: Bavisant
CAS#: 929622-08-2 (free base)
Chemical Formula: C19H27N3O2
Exact Mass: 329.2103
Molecular Weight: 329.444
Elemental Analysis: C, 69.27; H, 8.26; N, 12.76; O, 9.71

Related CAS #: 929622-08-2 (free base)   1103522-80-0 (HCl)    

Synonym: JNJ-31001074; JNJ31001074; JNJ 31001074; Bavisant.

IUPAC/Chemical Name: (4-cyclopropylpiperazin-1-yl)(4-(morpholinomethyl)phenyl)methanone


InChi Code: 1S/C19H27N3O2/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20/h1-4,18H,5-15H2


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

929622-08-2(Bavisant free base)
1103522-80-0 (Bavisant 2HCl)


1: Weisler RH, Pandina GJ, Daly EJ, Cooper K, Gassmann-Mayer C; 31001074-ATT2001
Study Investigators. Randomized clinical study of a histamine H3 receptor
antagonist for the treatment of adults with attention-deficit hyperactivity
disorder. CNS Drugs. 2012 May 1;26(5):421-34. doi:
10.2165/11631990-000000000-00000. PubMed PMID: 22519922.