WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 407250
CAS#: 449173-19-7
Description: VPC-23019 is a sphingosine-1-phosphate receptor antagonist. VPC-23019 acts as a competitive antagonist at both S1P1 and S1P3 receptors (pKis = 7.86 and 5.93, respectively). VPC-23019 can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells.
MedKoo Cat#: 407250
Name: VPC-23019
CAS#: 449173-19-7
Chemical Formula: C17H29N2O5P
Exact Mass: 372.1814
Molecular Weight: 372.4018
Elemental Analysis: C, 54.83; H, 7.85; N, 7.52; O, 21.48; P, 8.32
Synonym: VPC-23019, VPC23019, VPC 23019
IUPAC/Chemical Name: (R)-2-amino-3-((3-octylphenyl)amino)-3-oxopropyl dihydrogen phosphate
InChi Key: MRUSUGVVWGNKFE-MRXNPFEDSA-N
InChi Code: InChI=1S/C17H29N2O5P/c1-2-3-4-5-6-7-9-14-10-8-11-15(12-14)19-17(20)16(18)13-24-25(21,22)23/h8,10-12,16H,2-7,9,13,18H2,1H3,(H,19,20)(H2,21,22,23)/t16-/m1/s1
SMILES Code: O=P(O)(OC[C@@H](N)C(NC1=CC=CC(CCCCCCCC)=C1)=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 372.4018 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
