Malonoben
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319530

CAS#: 10537-47-0

Description: Malonoben, also known as AG-17 or Tyrphostin-9, is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 460 µM in the human epidermoid carcinoma cell line A431.


Chemical Structure

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Malonoben
CAS# 10537-47-0

Theoretical Analysis

MedKoo Cat#: 319530
Name: Malonoben
CAS#: 10537-47-0
Chemical Formula: C18H22N2O
Exact Mass: 282.17
Molecular Weight: 282.387
Elemental Analysis: C, 76.56; H, 7.85; N, 9.92; O, 5.67

Price and Availability

Size Price Availability Quantity
100mg USD 450 2 weeks
200mg USD 750 2 weeks
500mg USD 1450 2 weeks
1g USD 2450 2 weeks
Bulk inquiry

Synonym: Tyrphostin-9; Tyrphostin 9; Tyrphostin 9; Malonoben; Tyrphostin AG-17; SF 6847; GCP 5126; RG-50872; NSC 242557; Tyrphostin A9

IUPAC/Chemical Name: 2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile

InChi Key: MZOPWQKISXCCTP-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H22N2O/c1-17(2,3)14-8-12(7-13(10-19)11-20)9-15(16(14)21)18(4,5)6/h7-9,21H,1-6H3

SMILES Code: N#C/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 282.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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