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MedKoo CAT#: 522454

CAS#: 1623101-11-0

Description: VU0483605 is a potent and selective positive allosteric modulator (PAM) of mGluR1, displaying EC50 values of 0.39 and 0.36 μM at human and rat receptors, respectively, and no activity as a mGlu4 PAM (EC50 >10 μM).

Price and Availability

Size Price Shipping out time Quantity
5mg USD 225 2 Weeks
10mg USD 365 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

VU0483605, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 522454
Name: VU0483605
CAS#: 1623101-11-0
Chemical Formula: C20H10Cl3N3O3
Exact Mass: 444.97877
Molecular Weight: 446.67
Elemental Analysis: C, 53.78; H, 2.26; Cl, 23.81; N, 9.41; O, 10.75

Synonym: VU0483605, VU-0483605, VU 048360

IUPAC/Chemical Name: 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide


InChi Code: InChI=1S/C20H10Cl3N3O3/c21-12-4-1-3-11-16(12)20(29)26(19(11)28)15-7-6-10(9-14(15)23)25-18(27)17-13(22)5-2-8-24-17/h1-9H,(H,25,27)

SMILES Code: O=C(C1=NC=CC=C1Cl)NC2=CC=C(N(C(C3=C4C=CC=C3Cl)=O)C4=O)C(Cl)=C2

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: