WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 522442

CAS#: 288250-47-5

Description: Y-320 is an orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.

Chemical Structure

CAS# 288250-47-5

Theoretical Analysis

MedKoo Cat#: 522442
Name: Y-320
CAS#: 288250-47-5
Chemical Formula: C27H29ClN6O2
Exact Mass: 504.20
Molecular Weight: 505.010
Elemental Analysis: C, 64.21; H, 5.79; Cl, 7.02; N, 16.64; O, 6.34

Price and Availability

Size Price Availability Quantity
100mg USD 1350
200mg USD 2150
500mg USD 2950
1g USD 3950
2g USD 5250
5g USD 8650
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Synonym: Y-320; Y320; Y 320

IUPAC/Chemical Name: 1-(4-chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-carboxamide


InChi Code: InChI=1S/C27H29ClN6O2/c1-19-25(18-30-34(19)24-5-2-21(28)3-6-24)27(35)31-22-4-7-26(20(16-22)17-29)33-10-8-23(9-11-33)32-12-14-36-15-13-32/h2-7,16,18,23H,8-15H2,1H3,(H,31,35)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 505.010000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Sun D, Flock T, Deupi X, Maeda S, Matkovic M, Mendieta S, Mayer D, Dawson RJ, Schertler GF, Babu MM, Veprintsev DB. Probing Gαi1 protein activation at single-amino acid resolution. Nat Struct Mol Biol. 2015 Sep;22(9):686-94. doi: 10.1038/nsmb.3070. Epub 2015 Aug 10. PubMed PMID: 26258638. 2: Lin X, Zhong S, Ye X, Liao Y, Yao F, Yang X, Sun B, Zhang J, Li Q, Gao Y, Wang Y, Liu J, Han B, Chin YE, Zhou BP, Deng J. EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer. Mol Cancer. 2014 Oct 14;13:233. doi: 10.1186/1476-4598-13-233. PubMed PMID: 25311788; PubMed Central PMCID: PMC4200229. 3: Klyuyeva A, Tuganova A, Popov KM. Allosteric coupling in pyruvate dehydrogenase kinase 2. Biochemistry. 2008 Aug 12;47(32):8358-66. doi: 10.1021/bi800631h. Epub 2008 Jul 16. PubMed PMID: 18627174; PubMed Central PMCID: PMC2568900. 4: Kane BE, McCurdy CR, Ferguson DM. Toward a structure-based model of salvinorin A recognition of the kappa-opioid receptor. J Med Chem. 2008 Mar 27;51(6):1824-30. doi: 10.1021/jm701040v. Epub 2008 Feb 23. PubMed PMID: 18293909. 5: Noviello CM, Benichou S, Guatelli JC. Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit. J Virol. 2008 Feb;82(3):1249-58. Epub 2007 Dec 5. PubMed PMID: 18057255; PubMed Central PMCID: PMC2224416. 6: Kane BE, Nieto MJ, McCurdy CR, Ferguson DM. A unique binding epitope for salvinorin A, a non-nitrogenous kappa opioid receptor agonist. FEBS J. 2006 May;273(9):1966-74. PubMed PMID: 16640560.