WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 407151
Description: A 77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25nM.
MedKoo Cat#: 407151
Chemical Formula: C18H14N4
Exact Mass: 286.12185
Molecular Weight: 286.33
Elemental Analysis: C, 75.50; H, 4.93; N, 19.57
Synonym: A77-01; A 77-01; A-77-01.
IUPAC/Chemical Name: 4-(5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline
InChi Key: KJTYZDORHCDZPS-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H,1H3,(H,20,22)
SMILES Code: CC1=CC=CC(=N1)C2=C(C=NN2)C3=CC=NC4=CC=CC=C34
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 286.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|