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MedKoo CAT#: 405250

CAS#: 55778-02-4

Description: WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist. WZ811 shows subnanomolar potency (EC50 = 0.3 nM) in an affinity binding assay. In addition, when subjected to in vitro functional evaluation, WZ811 efficiently inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cyclic adenosine monophophate (cAMP) levels (EC50 = 1.2 nM) and SDF-1 induced Matrigel invasion (EC50 = 5.2 nM). The chemical structure of WZ811 is very similar to that of MSX-122.

Price and Availability

Size Price Shipping out time Quantity
25mg USD 150 2 Weeks
50mg USD 250 2 Weeks
100mg USD 350 2 Weeks
200mg USD 550 2 Weeks
500mg USD 850 2 Weeks
1g USD 1450 2 Weeks
2g USD 2250 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-06-06. Prices are subject to change without notice.

WZ811, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide).

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 405250
Name: WZ811
CAS#: 55778-02-4
Chemical Formula: C18H18N4
Exact Mass: 290.15315
Molecular Weight: 290.36
Elemental Analysis: C, 74.46; H, 6.25; N, 19.30

Synonym: WZ811; WZ-811; WZ 811.

IUPAC/Chemical Name: N,N'-(1,4-phenylenebis(methylene))bis(pyridin-2-amine)


InChi Code: InChI=1S/C18H18N4/c1-3-11-19-17(5-1)21-13-15-7-9-16(10-8-15)14-22-18-6-2-4-12-20-18/h1-12H,13-14H2,(H,19,21)(H,20,22)


Technical Data

White solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Related CAS#
55778-02-4 (WZ811 free base);
898190-81-3 (WZ811-2HCl salt);
897658-02-5(WZ811-4HCl salt)


1: Kawatkar SP, Yan M, Gevariya H, Lim MY, Eisold S, Zhu X, Huang Z, An J. Computational analysis of the structural mechanism of inhibition of chemokine receptor CXCR4 by small molecule antagonists. Exp Biol Med (Maywood). 2011 Jul 1;236(7):844-50. doi: 10.1258/ebm.2011.010345. Epub 2011 Jun 22. PubMed PMID: 21697335.