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MedKoo CAT#: 406301

CAS#: 160141-09-3

Description: L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-05. Prices are subject to change without notice.

L-744832 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 406301
Name: L-744832
CAS#: 160141-09-3
Chemical Formula: C26H45N3O6S2
Exact Mass: 559.27498
Molecular Weight: 559.782
Elemental Analysis: C, 55.79; H, 8.10; N, 7.51; O, 17.15; S, 11.46

Synonym: L744832; L 744832; L-744832

IUPAC/Chemical Name: (S)-isopropyl 2-((S)-2-(((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)oxy)-3-phenylpropanamido)-4-(methylsulfonyl)butanoate


InChi Code: InChI=1S/C26H45N3O6S2/c1-6-19(4)23(28-15-21(27)17-36)16-34-24(14-20-10-8-7-9-11-20)25(30)29-22(12-13-37(5,32)33)26(31)35-18(2)3/h7-11,18-19,21-24,28,36H,6,12-17,27H2,1-5H3,(H,29,30)/t19-,21+,22-,23+,24-/m0/s1

SMILES Code: O=C(OC(C)C)[C@@H](NC([C@@H](OC[C@@H](NC[C@@H](N)CS)[C@@H](C)CC)CC1=CC=CC=C1)=O)CCS(=O)(C)=O

Technical Data

Solid powder


Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>5 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information



 1: Spindler SR, Li R, Dhahbi JM, Yamakawa A, Mote P, Bodmer R, Ocorr K, Williams
RT, Wang Y, Ablao KP. Statin treatment increases lifespan and improves cardiac
health in Drosophila by decreasing specific protein prenylation. PLoS One.
2012;7(6):e39581. doi: 10.1371/journal.pone.0039581. Epub 2012 Jun 21. PubMed
PMID: 22737247; PubMed Central PMCID: PMC3380867.

2: Murphy LA, Moore T, Nesnow S. Propiconazole-enhanced hepatic cell
proliferation is associated with dysregulation of the cholesterol biosynthesis
pathway leading to activation of Erk1/2 through Ras farnesylation. Toxicol Appl
Pharmacol. 2012 Apr 15;260(2):146-54. doi: 10.1016/j.taap.2012.02.003. Epub 2012
Feb 14. PubMed PMID: 22361350.