WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 206206
CAS#: 1610537-15-9
Description: Seviteronel, also known as VT-464 and INO-464, is an orally available non-steroidal, lyase-selective inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase (CYP17A1 or CYP17), with potential anti-androgenic and antineoplastic activities. Upon oral administration, CYP17 inhibitor VT-464 selectively inhibits the enzymatic activity of the cytochrome P450 C17,20 lyase in both the testes and adrenal glands, thereby inhibiting androgen production.
MedKoo Cat#: 206206
Name: Seviteronel
CAS#: 1610537-15-9
Chemical Formula: C18H17F4N3O3
Exact Mass: 399.1206
Molecular Weight: 399.34
Elemental Analysis: C, 54.14; H, 4.29; F, 19.03; N, 10.52; O, 12.02
Synonym: VT464; VT 464; VT-464; INO-464; INO 464; INO464; Seviteronel.
IUPAC/Chemical Name: (S)-1-(6,7-bis(difluoromethoxy)naphthalen-2-yl)-2-methyl-1-(1H-1,2,3-triazol-5-yl)propan-1-ol
InChi Key: ZBRAJOQFSNYJMF-SFHVURJKSA-N
InChi Code: InChI=1S/C18H17F4N3O3/c1-9(2)18(26,15-8-23-25-24-15)12-4-3-10-6-13(27-16(19)20)14(28-17(21)22)7-11(10)5-12/h3-9,16-17,26H,1-2H3,(H,23,24,25)/t18-/m0/s1
SMILES Code: O[C@@](C(C)C)(C1=CC=C2C=C(OC(F)F)C(OC(F)F)=CC2=C1)C3=CN=NN3
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