WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 124030

CAS#: 33457-62-4

Description: Alnustone is a naturally occurring compound found in the rhizomes of Curcuma xanthorrhiza. Alnustone exhibits anti-inflammatory, antihepatotoxic and antiemetic activities.

Chemical Structure

CAS# 33457-62-4

Theoretical Analysis

MedKoo Cat#: 124030
Name: Alnustone
CAS#: 33457-62-4
Chemical Formula: C19H18O
Exact Mass: 262.14
Molecular Weight: 262.350
Elemental Analysis: C, 86.99; H, 6.92; O, 6.10

Price and Availability

Size Price Availability Quantity
10mg USD 350 2 Weeks
25mg USD 550 2 Weeks
50mg USD 950 2 Weeks
100mg USD 1650 2 Weeks
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Synonym: Alnustone; 33457-62-4; (4E,6E)-1,7-diphenylhepta-4,6-dien-3-one; CHEMBL461082; (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one

IUPAC/Chemical Name: (4E,6E)-1,7-diphenylhepta-4,6-dien-3-one


InChi Code: InChI=1S/C19H18O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-14H,15-16H2/b13-7+,14-8+

SMILES Code: O=C(CCc1ccccc1)/C=C/C=C/c1ccccc1

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 262.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang
J, Yang X, Lin X, Cao S. Alnustone inhibits the growth of hepatocellular
carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis. Phytother Res. 2022
Jan;36(1):525-542. doi: 10.1002/ptr.7337. Epub 2021 Nov 30. PMID: 34847624.

2: Zhang C, Deng Y, Wang X, Shi L, Zhan B, Hou N, Liu S, Bao M, Chi G, Fang T.
Alnustone inhibits Streptococcus pneumoniae virulence by targeting pneumolysin
and sortase A. Fitoterapia. 2022 Oct;162:105261. doi:
10.1016/j.fitote.2022.105261. Epub 2022 Aug 6. PMID: 35944753.

3: Song Y, Zhou Y, Yan XT, Bi JB, Qiu X, Bian Y, Wang KF, Zhang Y, Feng XS.
Pharmacokinetics and Tissue Distribution of Alnustone in Rats after Intravenous
Administration by Liquid Chromatography-Mass Spectrometry. Molecules. 2019 Sep
2;24(17):3183. doi: 10.3390/molecules24173183. PMID: 31480657; PMCID:

4: Li Z. Comment on: Alnustone inhibits the growth of hepatocellular carcinoma
via reactive oxygen species-mediated PI3K/Akt/mTOR/p70S6K axis. Phytother Res.
2023 Jun;37(6):2215-2216. doi: 10.1002/ptr.7708. Epub 2022 Dec 22. PMID: