WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 556323
Description: WAY-272077 is a Sphingosine kinase (SphK1, SphK2) inhibitor.
MedKoo Cat#: 556323
Chemical Formula: C14H14N2O3S
Exact Mass: 290.0725
Molecular Weight: 290.337
Elemental Analysis: C, 57.92; H, 4.86; N, 9.65; O, 16.53; S, 11.04
Synonym: WAY-272077; WAY272077; WAY 272077;
IUPAC/Chemical Name: (2E)-3-(3,4-Dimethoxyphenyl)-N-2-thiazolyl-2-propenamide
InChi Key: SMRXKMFZQYOXSX-GQCTYLIASA-N
InChi Code: InChI=1S/C14H14N2O3S/c1-18-11-5-3-10(9-12(11)19-2)4-6-13(17)16-14-15-7-8-20-14/h3-9H,1-2H3,(H,15,16,17)/b6-4+
SMILES Code: O=C(NC1=NC=CS1)/C=C/C2=CC=C(OC)C(OC)=C2
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 290.337 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
Sphingosine kinases (SphK1, SphK2) are main regulators of sphingosine-1-phosphate (S1P), which is a pleiotropic lipid mediator involved in numerous physiol. and pathophysiol. functions. SphKs are targets for novel anticancer and anti-inflammatory agents that can promote cell apoptosis and modulate autoimmune diseases.