WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 123236
Description: 1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker and also a alkyl chain-based PROTAC linker
MedKoo Cat#: 123236
Chemical Formula: C8H15NO3
Exact Mass: 173.11
Molecular Weight: 173.21
Elemental Analysis: C, 55.47; H, 8.73; N, 8.09; O, 27.71
Synonym: 141699-55-0; tert-butyl 3-hydroxyazetidine-1-carboxylate; 1-Boc-3-hydroxyazetidine; 1-n-boc-3-hydroxyazetidine; N-Boc-3-hydroxyazetidine
IUPAC/Chemical Name: tert-butyl 3-hydroxyazetidine-1-carboxylate
InChi Key: XRRXRQJQQKMFBC-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H15NO3/c1-8(2,3)12-7(11)9-4-6(10)5-9/h6,10H,4-5H2,1-3H3
SMILES Code: O=C(N1CC(C1)O)OC(C)(C)C
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 173.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|