TGN-020 sodium

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MedKoo CAT#: 123094

CAS#: 1313731-99-5

Description: TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor

Chemical Structure

TGN-020 sodium
CAS# 1313731-99-5

Theoretical Analysis

MedKoo Cat#: 123094
Name: TGN-020 sodium
CAS#: 1313731-99-5
Chemical Formula: C8H5N4NaOS
Exact Mass: 228.01
Molecular Weight: 228.2
Elemental Analysis: C, 42.11; H, 2.21; N, 24.55; Na, 10.07; O, 7.01; S, 14.05

Price and Availability

Size Price Availability Quantity
10.0mg USD 350.0 2 Weeks
50.0mg USD 750.0 2 Weeks
100.0mg USD 1250.0 2 Weeks
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Synonym: TGN-020 sodium; CID 139592827; TGN020 sodium; TGN-020;

IUPAC/Chemical Name: sodium nicotinoyl(1,3,4-thiadiazol-2-yl)amide


InChi Code: InChI=1S/C8H6N4OS.Na/c13-7(6-2-1-3-9-4-6)11-8-12-10-5-14-8;/h1-5H,(H,11,12,13);/q;+1/p-1

SMILES Code: O=C([N-]C1=NN=CS1)C2=CC=CN=C2.[Na+]

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 228.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Chiang PP, Kuo SP, Newman EA. Cellular mechanisms mediating activity-
dependent extracellular space shrinkage in the retina. Glia. 2022
Oct;70(10):1927-1937. doi: 10.1002/glia.24228. Epub 2022 Jun 9. PMID: 35678626;
PMCID: PMC9378592.