WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 123023
CAS#: 1002801-51-5
Description: TH 10785 is an 8-oxo guanine DNA glycosylase 1 (OGG1) activator. It binds in the active site of OGG1 and increases its recruitment to oxidative DNA damage and its repair.
MedKoo Cat#: 123023
Name: TH 10785
CAS#: 1002801-51-5
Chemical Formula: C17H21N3
Exact Mass: 267.17
Molecular Weight: 267.38
Elemental Analysis: C, 76.37; H, 7.92; N, 15.72
Synonym: TH 10785; TH-10785; TH10785
IUPAC/Chemical Name: N-Cyclohexyl-2-cyclopropyl-4-quinazolinamine
InChi Key: ZQMGQZOHIDOPCQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H21N3/c1-2-6-13(7-3-1)18-17-14-8-4-5-9-15(14)19-16(20-17)12-10-11-12/h4-5,8-9,12-13H,1-3,6-7,10-11H2,(H,18,19,20)
SMILES Code: C1(C2CC2)=NC(NC3CCCCC3)=C4C=CC=CC4=N1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 267.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
