WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 556210
CAS#: 333357-56-5
Description: WAY-299838 is a useful chemical agent for chemical synthesis of hypoxia-inducible factor-1 inhibitor. It was reported in Bioorganic & Medicinal Chemistry (2014), 22(19), 5513-5529.
MedKoo Cat#: 556210
Name: WAY-299838
CAS#: 333357-56-5
Chemical Formula: C18H19IN2O2
Exact Mass: 422.0491
Molecular Weight: 422.2665
Elemental Analysis: C, 51.20; H, 4.54; I, 30.05; N, 6.63; O, 7.58
Synonym: WAY-299838; WAY 299838; WAY299838;
IUPAC/Chemical Name: Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
InChi Key: ZOFBYPLMJZJZIK-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H19IN2O2/c19-16-5-7-17(8-6-16)20-18(22)15-3-1-14(2-4-15)13-21-9-11-23-12-10-21/h1-8H,9-13H2,(H,20,22)
SMILES Code: O=C(NC1=CC=C(I)C=C1)C2=CC=C(CN3CCOCC3)C=C2
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 422.2665 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors
By: Nagao, Satoshi; Yamane, Yoshinobu; Funasaka, Setsuo; Tanaka, Keigo; Miyazaki, Kazuki; Kotake, Yoshihiko; Kamata, Jun-ichi; Watanabe-Miyano, Saori; Toyama, Osamu; Ozawa, Yoichi; et al
Bioorganic & Medicinal Chemistry (2014), 22(19), 5513-5529
