WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 130150


Description: C4E8 is a selective α-glucosidase inhibitor.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 130150
Name: C4E8
Chemical Formula: C20H15N3O3
Exact Mass: 345.11
Molecular Weight: 345.358
Elemental Analysis: C, 69.56; H, 4.38; N, 12.17; O, 13.90

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: C4E8

IUPAC/Chemical Name: (E)-N'-((6-methyl-4-oxo-4H-chromen-3-yl)methylene)-1H-indole-2-carbohydrazide


InChi Code: InChI=1S/C20H15N3O3/c1-12-6-7-18-15(8-12)19(24)14(11-26-18)10-21-23-20(25)17-9-13-4-2-3-5-16(13)22-17/h2-11,22H,1H3,(H,23,25)/b21-10+

SMILES Code: O=C(C(N1)=CC2=C1C=CC=C2)N/N=C/C3=COC4=C(C=C(C)C=C4)C3=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 345.358000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Wu Y, Liu C, Hu L. Fragment-Based Dynamic Combinatorial Chemistry for Identification of Selective α-Glucosidase Inhibitors. ACS Med Chem Lett. 2022 Oct 19;13(11):1791-1796. doi: 10.1021/acsmedchemlett.2c00405. PMID: 36385930; PMCID: PMC9661702.