WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122630
Description: Y08175 is a CBP/P300 BRD inhibitor
MedKoo Cat#: 122630
Chemical Formula: C23H19FN4O5
Exact Mass: 450.13
Molecular Weight: 450.43
Elemental Analysis: C, 61.33; H, 4.25; F, 4.22; N, 12.44; O, 17.76
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Note: Price will be listed if it is available in the future.
Synonym: Y08175; Y 08175; Y-08175
IUPAC/Chemical Name: 3-(1-acetyl-5-methoxy-1H-indole-3-carboxamido)-4-fluoro-5-(1-methyl-1H-pyrazol-4-yl)benzoic acid
InChi Key: RCPJEOKKJODBRQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H19FN4O5/c1-12(29)28-11-18(17-8-15(33-3)4-5-20(17)28)22(30)26-19-7-13(23(31)32)6-16(21(19)24)14-9-25-27(2)10-14/h4-11H,1-3H3,(H,26,30)(H,31,32)
SMILES Code: COC1=CC=C(N(C(C)=O)C=C2C(NC3=CC(C(O)=O)=CC(C4=CN(C)N=C4)=C3F)=O)C2=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 450.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
. Xiang Q, et al. Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J Med Chem. 2022;65(1):785-810.