WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122630

CAS#: 2223014-57-9

Description: Y08175 is a CBP/P300 BRD inhibitor

Chemical Structure

CAS# 2223014-57-9

Theoretical Analysis

MedKoo Cat#: 122630
Name: Y08175
CAS#: 2223014-57-9
Chemical Formula: C23H19FN4O5
Exact Mass: 450.13
Molecular Weight: 450.430
Elemental Analysis: C, 61.33; H, 4.25; F, 4.22; N, 12.44; O, 17.76

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Y08175; Y 08175; Y-08175

IUPAC/Chemical Name: 3-(1-acetyl-5-methoxy-1H-indole-3-carboxamido)-4-fluoro-5-(1-methyl-1H-pyrazol-4-yl)benzoic acid


InChi Code: InChI=1S/C23H19FN4O5/c1-12(29)28-11-18(17-8-15(33-3)4-5-20(17)28)22(30)26-19-7-13(23(31)32)6-16(21(19)24)14-9-25-27(2)10-14/h4-11H,1-3H3,(H,26,30)(H,31,32)

SMILES Code: COC1=CC=C(N(C(C)=O)C=C2C(NC3=CC(C(O)=O)=CC(C4=CN(C)N=C4)=C3F)=O)C2=C1

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 450.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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[1]. Xiang Q, et al. Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J Med Chem. 2022;65(1):785-810.