18:1 TAP (DOTAP, MS Salt)

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122222

CAS#: 144189-73-1

Description: 18:1 TAP (DOTAP, MS Salt) is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails with single alkene groups in each tail. 18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.

Chemical Structure

18:1 TAP (DOTAP, MS Salt)
CAS# 144189-73-1

Theoretical Analysis

MedKoo Cat#: 122222
Name: 18:1 TAP (DOTAP, MS Salt)
CAS#: 144189-73-1
Chemical Formula: C43H83NO8S
Exact Mass: 773.5839
Molecular Weight: 774.2
Elemental Analysis: C, 66.71; H, 10.81; N, 1.81; O, 16.53; S, 4.14

Price and Availability

Size Price Availability Quantity
10.0mg USD 450.0 2 Weeks
25.0mg USD 750.0 2 Weeks
50.0mg USD 1150.0 2 Weeks
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Synonym: DOTAP; 1,2-dioleoyl-3-trimethylammoniumpropane; 1,2-DOTAP

IUPAC/Chemical Name: N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate


InChi Code: InChI=1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;


Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 774.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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