WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122222
CAS#: 144189-73-1
Description: 18:1 TAP (DOTAP, MS Salt) is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails with single alkene groups in each tail. 18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.
MedKoo Cat#: 122222
Name: 18:1 TAP (DOTAP, MS Salt)
CAS#: 144189-73-1
Chemical Formula: C43H83NO8S
Exact Mass: 773.5839
Molecular Weight: 774.2
Elemental Analysis: C, 66.71; H, 10.81; N, 1.81; O, 16.53; S, 4.14
Synonym: DOTAP; 1,2-dioleoyl-3-trimethylammoniumpropane; 1,2-DOTAP
IUPAC/Chemical Name: N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate
InChi Key: RSMRWWHFJMENJH-LQDDAWAPSA-M
InChi Code: InChI=1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
SMILES Code: [O-]S(OC)(=O)=O.C[N+](C)(C)CC(OC(CCCCCCC/C=C\CCCCCCCC)=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 774.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
