WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122218
CAS#: 72719-84-7
Description: 14:0 DAP, 1,2-dimyristoyl-3-dimethylammonium-propane, is a cationic lipid that can be used to formulate lipid nanoparticles (LNPs). 18:0 DAP also serves as a pH-sensitive transfection reagent.
MedKoo Cat#: 122218
Name: 14:0 DAP
CAS#: 72719-84-7
Chemical Formula: C33H65NO4
Exact Mass: 539.4914
Molecular Weight: 539.89
Elemental Analysis: C, 73.42; H, 12.14; N, 2.59; O, 11.85
Synonym: 3-(DImethylamino)propane-1,2-diyl ditetradecanoate; 14:0 DAP, 1,2-dimyristoyl-3-dimethylammonium-propane, powder; 14:0 DAP, 1,2-dimyristoyl-3-dimethylammonium-propane, chloroform
IUPAC/Chemical Name: 3-(dimethylamino)propane-1,2-diyl ditetradecanoate
InChi Key: QUQHEMSUWCJRBP-UHFFFAOYSA-N
InChi Code: InChI=1S/C33H65NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-32(35)37-30-31(29-34(3)4)38-33(36)28-26-24-22-20-18-16-14-12-10-8-6-2/h31H,5-30H2,1-4H3
SMILES Code: CCCCCCCCCCCCCC(OC(CN(C)C)COC(CCCCCCCCCCCCC)=O)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 539.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
