WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122200

CAS#: 2496687-00-2

Description: Thalidomide-5-(C6-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU.

Chemical Structure

CAS# 2496687-00-2

Theoretical Analysis

MedKoo Cat#: 122200
Name: Thalidomide-5-(C6-amine)
CAS#: 2496687-00-2
Chemical Formula: C20H24N4O5
Exact Mass: 400.17
Molecular Weight: 400.440
Elemental Analysis: C, 59.99; H, 6.04; N, 13.99; O, 19.98

Price and Availability

Size Price Availability Quantity
100mg USD 700 2 Weeks
250mg USD 1250 2 Weeks
500mg USD 2000 2 Weeks
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Synonym: Thalidomide-O-amido-PEG4-propargyl

IUPAC/Chemical Name: N-(6-aminohexyl)-2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carboxamide


InChi Code: InChI=1S/C20H24N4O5/c21-9-3-1-2-4-10-22-17(26)12-5-6-13-14(11-12)20(29)24(19(13)28)15-7-8-16(25)23-18(15)27/h5-6,11,15H,1-4,7-10,21H2,(H,22,26)(H,23,25,27)


Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 400.440000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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