APC-300

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 205814

CAS#: NONE

Description: APC-300 is a natural compound that, in pre-clinical studies, has been shown to not only inhibit the growth, but also stimulates the death of human prostate cancer cells. APC-300 is a small molecule signal transduction inhibitor that acts as an anti-inflammatory agent and blocks prostate cancer progression in in vivo models of the disease. In addition to prostate cancer, APC-300 has also demonstrated efficacy in disease models of human melanoma and pancreatic cancer. Adamis believes that APC-300 may have potential applications in the treatment of several tumor types. APC-300 is currently in preclinical development.


Chemical Structure

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APC-300
CAS# NONE

Theoretical Analysis

MedKoo Cat#: 205814
Name: APC-300
CAS#: NONE
Chemical Formula:
Exact Mass:
Molecular Weight:
Elemental Analysis:

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: APC300; APC-300; APC 300

IUPAC/Chemical Name: NONE

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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 1: Manner H, Enderle MD, Pech O, May A, Plum N, Riemann JF, Ell C, Eickhoff A. Second-generation argon plasma coagulation: two-center experience with 600 patients. J Gastroenterol Hepatol. 2008 Jun;23(6):872-8. doi: 10.1111/j.1440-1746.2008.05437.x. PubMed PMID: 18565020.

2: Manner H, May A, Faerber M, Pech O, Plum N, Ell C. The tissue effect of second generation argon plasma coagulation (VIO APC) in comparison to standard APC and Nd:YAG laser in vitro. Acta Gastroenterol Belg. 2007 Oct-Dec;70(4):352-6. PubMed PMID: 18330091.

3: Dang BW, Zhang J. [The efficacy of endobronchial argon plasma coagulation in the management of intraluminal obstructive lesions of the central airway]. Zhonghua Jie He He Hu Xi Za Zhi. 2007 May;30(5):330-3. Chinese. PubMed PMID: 17651635.

4: Nomura T, Miyashita M, Makino H, Maruyama H, Katsuta M, Kashiwabara M, Takahashi K, Sasajima K, Yamashita K, Tajiri T. Argon plasma coagulation for the treatment of superficial esophageal carcinoma. J Nippon Med Sch. 2007 Apr;74(2):163-7. PubMed PMID: 17507793.

5: Miyazawa T, Nawashiro H, Shima K, Bertalanffy H. Early experiences of haemostasis on brain tumour surgery with Argon Plasma Coagulation (APC). Acta Neurochir (Wien). 2000;142(11):1247-51. PubMed PMID: 11201639.

6: Roach SK, Kozarek RA, Raltz SL, Sumida SE. In vitro evaluation of integrity and sterilization of single-use argon beam plasma coagulation probes. Am J Gastroenterol. 1999 Jan;94(1):139-43. PubMed PMID: 9934744.

7: Katsuura Y, Aoki K, Tanabe H, Kiyoki M, Funatsu A. Characteristic effects of activated human protein C on tissue thromboplastin-induced disseminated intravascular coagulation in rabbits. Thromb Res. 1994 Nov 15;76(4):353-62. PubMed PMID: 7871494.



Additional Information